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miRSystem specifications

Information


Unique identifier OMICS_05796
Name miRSystem
Restrictions to use None
Database management system MySQL
Data access Browse
Maintained Yes

Taxon


  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus

Maintainer


  • person_outline Eric Y. Chuang

Publication for miRSystem

miRSystem citations

 (4)
library_books

Identification of Long Noncoding RNAs Deregulated in Papillary Thyroid Cancer and Correlated with BRAFV600E Mutation by Bioinformatics Integrative Analysis

2017
Sci Rep
PMCID: 5431778
PMID: 28490781
DOI: 10.1038/s41598-017-01957-0

[…] se for Annotation, Visualization and Integrated Discovery (DAVID), which returned the gene ontology of the query genes and identified enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways. miRSystem was used to calculate enriched pathways based on the predicted targets of the query microRNAs, which in this case, were the DE microRNAs in both conditions (Normal × Tumor and WT × BRAFV600E […]

library_books

Human adipose mesenchymal stem cell derived exosomal miRNAs are critical factors for inducing anti proliferation signalling to A2780 and SKOV 3 ovarian cancer cells

2016
Sci Rep
PMCID: 5143979
PMID: 27929108
DOI: 10.1038/srep38498

[…] GO functional enrichment analysis was performed to verify predicted target genes against the PANTHER DNA database (http://pantherdb.org/). KEGG and BioCarta analyses were performed against the miRsystem RNA database, which integrates information from several pathway prediction programs, including KEGG (http://www.kegg.jp/), BioCarta (http://cgap.nci.nih.gov/Pathways/BioCarta_Pathways), Reac […]

library_books

Bioinformatic tools for microRNA dissection

2015
Nucleic Acids Res
PMCID: 4705652
PMID: 26578605
DOI: 10.1093/nar/gkv1221

[…] al pathway regulation by (i) an enrichment analysis of miRNA target genes and (ii) using a proximity score to evaluate the functional role of miRNAs in biological pathways by their network proximity. MiRSystem () is a web-based tool providing miRNA target gene analysis, prediction of biological functions, and canonical pathways of miRNAs and their target genes. DIANA-miRPath (,,) is a relatively e […]

library_books

Genetic variation in the 3′ UTR of CYP1A2, CYP2B6, CYP2D6, CYP3A4, NR1I2, and UGT2B7: potential effects on regulation by microRNA and pharmacogenomics relevance

2014
Front Genet
PMCID: 4044583
PMID: 24926315
DOI: 10.3389/fgene.2014.00167

[…] remains as to what is the appropriate minimum number or combination of algorithms to pick most microRNAs. MicroRNA prediction using 7 of the 15 algorithms (miR2Gene—DIANA-microT v.3, miRanda-MirSVR, miRSystem, PACCMIT, PITA, TargetScan, and TargetSpy), showed on average 83% (range 43–98%) of all unique microRNAs, pointing toward the major contribution of these seven algorithms (especially TargetS […]

Citations

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miRSystem institution(s)
YongLin Biomedical Engineering Center, National Taiwan University, Taipei, Taiwan; Bioinformatics and Biostatistics Core, Center of Genomic Medicine, National Taiwan University, Taipei, Taiwan; Graduate Institute of Biomedical Electronics and Bioinformatics and Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan; Institute of Biotechnology, National Taiwan University, Taipei, Taiwan; Department of Public Health, National Taiwan University, Taipei, Taiwan; Graduate Institute of Physiology, National Taiwan University, Taipei, Taiwan
miRSystem funding source(s)
This research was supported in part by NSC100-2314-B-002-054- from National Science Council, Taiwan and 99R81811 by National Taiwan University, Taiwan.

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