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miRTar specifications


Unique identifier OMICS_00410
Name miRTar
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • Primates
    • Homo sapiens


  • person_outline Hsien-Da Huang

Publication for miRTar

miRTar citations


A Semi Supervised Learning Algorithm for Predicting Four Types MiRNA Disease Associations by Mutual Information in a Heterogeneous Network

PMCID: 5867860
PMID: 29498680
DOI: 10.3390/genes9030139

[…] irculating miRNAs, epigenetics, miRNA-target interactions and genetics, whose number recorded in the HMDD has increased remarkably. As for interactions between miRNAs and targeted genes, for example, miRTar [], an integrated system, identifies miRNA-target interactions in various scenarios and analyzes miRNA-targeted genes in pathways. In order to improve the accuracy of miRNA-gene target interact […]


High Expression of TET1 Predicts Poor Survival in Cytogenetically Normal Acute Myeloid Leukemia From Two Cohorts

PMCID: 5835576
PMID: 29402726
DOI: 10.1016/j.ebiom.2018.01.031

[…] g by Cytoscape software (). The toppgene analysis was done on the platform (https://toppgene.cchmc.org/prioritization.jsp). Interaction of miRNA and mRNA integrative analyses in silico were using the mirtar platform (http://mirtar.mbc.nctu.edu.tw/human/index.php). All statistical analyses were conducted with R statistic packages, version 3.4.1 (www.r-project.org). The two-sided level of significan […]


Comprehensive Characterization of the RNA Editomes in Cancer Development and Progression

Front Genet
PMCID: 5776088
PMID: 29387082
DOI: 10.3389/fgene.2017.00230

[…] e editing sites in 3′ UTR were significantly enriched in microRNA targets (p-value ∼ 0, hypergeometric test). Specifically, 52 and 44% editing sites in 3′ UTR were microRNA targets which predicted by miRTar () for poly(A)+ and poly(A)- RNAs respectively (Figure ). The top 10 miRNAs according to the number of edited targets were shown in Table . In addition, more than half of the sites in coding re […]


Influence of Adalimumab on the Expression Profile of Genes Associated with the Histaminergic System in the Skin Fibroblasts In Vitro

Biomed Res Int
PMCID: 5816894
PMID: 29487864
DOI: 10.1155/2018/1582173

[…] The bioinformatic resources of the miRTar database have allowed to determine which of the differentiating microRNAs correlated to the mRNAs differentiating the fibroblasts exposed to the drug from the control group. Based on the miRNA […]


Bortezomib induced miRNAs direct epigenetic silencing of locus genes and trigger apoptosis in leukemia

PMCID: 5775404
PMID: 29120412
DOI: 10.1038/cddis.2017.520

[…] otic role, remain poorly understood. We first performed miRNA and mRNA microarray analysis in THP-1 cells to explore the link between CEBPD-regulated miRNAs and mRNAs. Using the public access program miRTar, we explored the correlation between the CEBPD-induced downregulated mRNA () and upregulated miRNA profiles (). Interestingly, among 490 CEBPD-downregulated mRNAs, 407 (83%) CEBPD-responsive mR […]


An Assessment of Database Validated microRNA Target Genes in Normal Colonic Mucosa: Implications for Pathway Analysis

Cancer Inform
PMCID: 5484592
PMID: 28690395
DOI: 10.1177/1176935117716405

[…] notype.,, We identified experimentally validated target gene these miRNAs using miRNA-mRNA pairs from miRTarBase v6.0. As our miRNA names are those from Agilent v19 (corresponding to miRBase v19) and miRTar-Base v6.0 includes newer associations, we determined the new nomenclature for any miRNAs whose names did not match using archived miRBase (http://www.mirbase.org) “miRNA.diff.zip” files.To dete […]


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miRTar institution(s)
Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsin-Chu, Taiwan; Department of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, Taiwan; Department of Computer Science and Engineering, Yuan Ze University, Chungli, Taiwan

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