miRTar protocols

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miRTar specifications

Information


Unique identifier OMICS_00410
Name miRTar
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline Hsien-Da Huang <>

Publication for miRTar

miRTar in pipelines

 (3)
2018
PMCID: 5835576
PMID: 29402726
DOI: 10.1016/j.ebiom.2018.01.031

[…] by cytoscape software (). the toppgene analysis was done on the platform (https://toppgene.cchmc.org/prioritization.jsp). interaction of mirna and mrna integrative analyses in silico were using the mirtar platform (http://mirtar.mbc.nctu.edu.tw/human/index.php). all statistical analyses were conducted with r statistic packages, version 3.4.1 (www.r-project.org). the two-sided level […]

2018
PMCID: 5908130
PMID: 29516617
DOI: 10.1111/jcmm.13570

[…] did not show significant concentration changes across samples., the biological impacts of ptl‐associated circulating mirnas were assessed using predicted and validated mirna‐mrna interactions from mirtar database., to focus on the possible functional changes in placenta, we filtered the mirna target gene list with protein/transcript enriched in placenta based on human protein atlas. to gain […]

2015
PMCID: 5380330
PMID: 25826780
DOI: 10.1038/srep09571

[…] we visualized the associations between target genes and mirnas\pathways by using functional classification 2-d view analysis module of david annotation tool. mirna-target interaction was analyzed by mirtar web server of human (http://mirtar.mbc.nctu.edu.tw/human/). we picked the mirna-target interactions in biological pathways of interest and used cytoscape for graphical representations., […]


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miRTar in publications

 (39)
PMCID: 5937496
PMID: 29760555
DOI: 10.2147/OTT.S158309

[…] between 539 crc samples and 11 normal samples. the interactions between delncrnas and demirnas were predicted by mircode. the demrnas targeted by the demirnas were retrieved according to targetscan, mirtar-base, and mirdb. the lncrna–mirna–mrna cerna network was constructed based on the demirna–delncrna and demirna–demrna interactions. functional enrichment analysis revealed the biological […]

PMCID: 5908130
PMID: 29516617
DOI: 10.1111/jcmm.13570

[…] mirnas identified from whole plasma, evs and ev‐depleted plasma, we conducted analysis to determine the perturbed networks represented by these dysregulated mirnas in ptl. based on targetscan and mirtar databases,, the 127 differentially expressed mirnas in ptl patient samples may interact with more than 11 000 different genes. to better reflect the changes of biological processes […]

PMCID: 5867860
PMID: 29498680
DOI: 10.3390/genes9030139

[…] mirnas, epigenetics, mirna-target interactions and genetics, whose number recorded in the hmdd has increased remarkably. as for interactions between mirnas and targeted genes, for example, mirtar [], an integrated system, identifies mirna-target interactions in various scenarios and analyzes mirna-targeted genes in pathways. in order to improve the accuracy of mirna-gene target […]

PMCID: 5776088
PMID: 29387082
DOI: 10.3389/fgene.2017.00230

[…] editing sites in 3′ utr were significantly enriched in microrna targets (p-value ∼ 0, hypergeometric test). specifically, 52 and 44% editing sites in 3′ utr were microrna targets which predicted by mirtar () for poly(a)+ and poly(a)- rnas respectively (figure ). the top 10 mirnas according to the number of edited targets were shown in table . in addition, more than half of the sites in coding […]

PMCID: 5816894
PMID: 29487864
DOI: 10.1155/2018/1582173

[…] of the fibroblast cells exposed to the drug, compared to the control sample, could potentially affect the transcriptional activity of the differentiating mrnas, the mirna target prediction tools mirtar (http://mirtar.mbc.nctu.edu.tw/human/predictionindex.php) and microrna.org (http://www.microrna.org/microrna/getgeneform.do) have been used., the xtt assay revealed that no cytotoxicity […]


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miRTar institution(s)
Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsin-Chu, Taiwan; Department of Biological Science and Technology, National Chiao Tung University, Hsin-Chu, Taiwan; Department of Computer Science and Engineering, Yuan Ze University, Chungli, Taiwan

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