miRTrail specifications


Unique identifier OMICS_13363
Name miRTrail
Interface Web user interface
Restrictions to use None
Input data miRBase identifiers for miRNAs and GeneSymbol identifiers for the mRNAs.
Programming languages C++, PHP
Computer skills Basic
Stability Stable
Java web server
Maintained Yes


  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus
  • Vertebrates
    • Danio rerio



  • person_outline Andreas Keller <>

Publication for miRTrail

miRTrail in publications

PMCID: 4460623
PMID: 26040466
DOI: 10.1186/1471-2164-16-S5-S2

[…] expressed genes (mrnas) involved three steps. first, for the set of differentially expressed mirnas, which were either up- or down-regulated between the tumor and normal samples, we used mirtrail [] via microcosm targets v5 (http://www.ebi.ac.uk/enright-srv/microcosm/htdocs/targets/v5/) to extract their target mrnas (regulated genes) and overlapped them with the identified […]

PMCID: 4261811
PMID: 25540777
DOI: 10.3389/fbioe.2014.00069

[…] transcriptor factors. mirconnx (huang et al., ), given a network of genes, transcriptor factors, and mirnas, extends it with further tf and mirna–gene intersections inferred by user expression data. mirtrail (laczny et al., ) analyzes the role of mirnas and genes deregulated in a disease by using a mirna-gene networks and expression data., in this work, we have imported and integrated […]

PMCID: 3663800
PMID: 23717626
DOI: 10.1371/journal.pone.0064543

[…] interaction predictions . recently, methods and web-services for the integrated analysis of mirna and mrna expression data have been developed such as magia , , mmia , miract , mirconnx and mirtrail . genmir++ implements a bayesian learning approach to identify differential mirna-mrna regulation , . hoctar calculates negative correlations between mirna and mrna expression . […]

PMCID: 3666437
PMID: 23762142
DOI: 10.1155/2013/510208

[…] (mirna) and mrna expression biomarkers for bss of ua. we identified 1081 mrnas and 25 mirnas differentially expressed between bss of ua patients and healthy controls by microarrays. we used david, mirtrail, and the protein-protein interactions method to explore the related pathways and networks of differentially expressed mirnas and mrnas. by combining the results of pathways and networks, […]

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miRTrail institution(s)
Center for Bioinformatics, Saarland University, Saarbrücken, Germany; Department of Human Genetics, Saarland University, Homburg/Saar, Germany; Department of Computer Sciences, University of Tuebingen, Tübingen, Germany; Department of Internal Medicine III, University of Heidelberg, Heidelberg, Germany; Siemens Healthcare, Erlangen, Germany
miRTrail funding source(s)
This work has been funded by DFG Priority Program SPP 1335: LE 952/3- 1, DFG LE 952/5-1, and by DFG Me 917/20-1.

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