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MIRU-VNTRplus specifications


Unique identifier OMICS_24291
Name MIRU-VNTRplus
Alternative name Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat plus
Software type Application/Script
Interface Web user interface
Restrictions to use None
Input data A single user strain.
Input format FASTA
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Thomas Weniger

Publications for Mycobacterial Interspersed Repetitive-Unit-Variable-Number Tandem-Repeat plus

MIRU-VNTRplus citations


Genetic diversity of drug and multidrug resistant Mycobacterium tuberculosis circulating in Veracruz, Mexico

PLoS One
PMCID: 5854261
PMID: 29543819
DOI: 10.1371/journal.pone.0193626

[…] genotypes were expressed as numerical codes representing the number of miru-vntr for each locus. lineages were individually identified using the similarity search module [] of the database miru-vntrplus (http://www.miru-vntrplus.org/miru/index.faces)[]., the tree polar arrangement was realized by the figtree program (tree figure drawing tool version 1.4.3. […]


Molecular Characterization of Mycobacterium avium subsp. hominissuis of Two Groups of Lymph Nodes, Being Intradermal Tuberculin or Interferon Gamma Test Positive and Negative, Isolated from Swiss Cattle at Slaughter

PMCID: 5844927
PMID: 29556502
DOI: 10.3389/fvets.2018.00032

[…] the discriminatory power of a genotyping method, was determined according to the formula described by hunter and gaston ()., genetic strain lineages were predicted using online tools available from miru-vntrplus website (). a dendrogram based on 20 vntr loci was generated using the unweighted pair group method using arithmetic averages (upgma) algorithm., variable number of tandem repeat data […]


Genetic Diversity of Drug resistant Mycobacterium tuberculosis Isolates in Isfahan Province of Iran

PMCID: 5840967
PMID: 29531921
DOI: 10.4103/2277-9175.225594

[…] copy numbers were obtained by comparing the band sizes with an allele naming table for each tandem repeat locus made available in microsoft excel format on the miru-vntr plus website (http://www.miru-vntrplus.org). the h37rv was used as control for allele assignation., the final result of 24-locus miru-vntr typing (miru-vntr data) is a numerical code, corresponding to the repeat number […]


A complex scenario of tuberculosis transmission is revealed through genetic and epidemiological surveys in Porto

BMC Infect Dis
PMCID: 5785791
PMID: 29370774
DOI: 10.1186/s12879-018-2968-1

[…]  ).fig. 1, we determined the main geographical lineages for the m. tuberculosis isolates by comparing the genotyped samples and the miru-vntr reference strains whose lineage is well determined in the miru-vntrplus website http://www.miru-vntrplus.org., isolates that share common genetic ancestry are referred to as genotypically clustered, a potential marker for episodes of direct tb transmission. […]


Genetic diversity and potential routes of transmission of Mycobacterium bovis in Mozambique

PLoS Negl Trop Dis
PMCID: 5772998
PMID: 29346413
DOI: 10.1371/journal.pntd.0006147

[…] in order to evaluate relatedness of the spoligotype and vntr patterns of the different samples we generated a dendogram using the upgma algorithm using the tool provided on the site http://www.miru-vntrplus.org/. the spoligotype patterns of the respective isolates were entered into the mbovis.org database. in this database each unique spoligotype pattern is named by 'sb' followed by a four […]


Convergent evolution and topologically disruptive polymorphisms among multidrug resistant tuberculosis in Peru

PLoS One
PMCID: 5744980
PMID: 29281674
DOI: 10.1371/journal.pone.0189838

[…] using principal component analysis. clades were named using the corresponding miru-vntr and spoligotype independently by the institut pasteur guadeloupe according to published protocols (www.miru-vntrplus.org and www.pasteur-guadeloupe.fr:8081/sitvit_online) []. ancestral state reconstruction was undertaken using maximum parsimony, likelihood and bayesian approaches., homoplastic […]

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MIRU-VNTRplus institution(s)
Department of Periodontology, University Hospital Munster, Munster, Germany; Molecular Mycobacteriology, Forschungszentrum Borstel, Borstel, Germany; CIIL – Center for Infection and Immunity of Lille INSERM U 1019, CNRS UMR 8204 Univ Lille Nord de France, Institut Pasteur de Lille, France
MIRU-VNTRplus funding source(s)
Supported by German Federal Ministry of Education and Research in the framework of the Network Zoonoses (grant number 01KI07124) and PathoGenomikPlus Network (grant number 0313801J).

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