Performs survival analyses and draws Kaplan–Meier (KM) plots for submitted ‘microRNA' across several available data sets, which cover more than 800 patients. A robust statistical procedure is implemented to account for multiple testing. MIRUMIR is incorporated into BioProfiling.de, analytical portal for high-throughput cell biology. MIRUMIR supports the need of biomedical researchers to estimate the power of miR to serve as potential biomarker to predict survival of cancer patients. MIRUMIR provides such analyses based on several publicly available clinical miR data sets annotated with patient survival information.
Medical Research Council Toxicology Unit, Leicester University, Leicester, UK; Department of Experimental Medicine and Surgery, University of Rome, Rome, Italy; Saint-Petersburg State Institute of Technology, Saint-Petersburg, Russia; Department of Biochemistry, University of Leicester, Leicester, UK; Institute of Cytology, Saint-Petersburg, Russia; Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia
MIRUMIR funding source(s)
This work was supported by the UK Medical Research Council (MRC) and funding from RFBS (10-04-01234), MCB RAS, Russian Federal grants 16.740.11.036 and 11.G34.31.0069.