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MirZ specifications

Information


Unique identifier OMICS_14639
Name MirZ
Interface Web user interface
Restrictions to use None
Programming languages Java
Computer skills Basic
Stability No
Maintained Yes

Taxon


  • Invertebrates
    • Caenorhabditis elegans
  • Primates
    • Homo sapiens

Maintainer


  • person_outline Mihaela Zavolan

Publication for MirZ

MirZ citations

 (6)
library_books

miR 20a regulates expression of the iron exporter ferroportin in lung cancer

2015
PMCID: 4803811
PMID: 26560875
DOI: 10.1007/s00109-015-1362-3

[…] were acquired using the fusion-fx system (vilber lourmat). flow cytometry analysis was done using the bd lsrfortessa cell analyzer (bd biosciences)., mirna expression atlas was generated using mirz (https://www.mirz.unibas.ch) []. potential mirna targets were predicted and analyzed using four publically available algorithms: miranda (http://www.microrna.org), targetscan […]

library_books

Experimental procedures to identify and validate specific mRNA targets of miRNAs

2015
PMCID: 4817421
PMID: 27047316
DOI: 10.17179/excli2015-319

[…] 3.0 (http://microrna.gr/microt) (maragkakis et al., 2009[]), targetscan (http://www.targetscan.org) (friedman et al., 2009[]), pictar (http://pictar.org) (lall et al., 2006[]), and elmmo (http://www.mirz.unibas.ch) (gaidatzis et al., 2007[]). the latest review article from this laboratory (vlachos and hatzigeorgiou, 2013[]) provided a detailed overview of the major mirna/mrna target […]

library_books

Genetic Variations Creating MicroRNA Target Sites in the FXN 3′ UTR Affect Frataxin Expression in Friedreich Ataxia

2013
PLoS One
PMCID: 3559822
PMID: 23382970
DOI: 10.1371/journal.pone.0054791

[…] and mirtif, which is a support vector machine-based mirna-target filtering-system to distinguish true predicted target sites from false ones . mirna expression profiling data were accessed through mirz and mimirna ., chi-square tests were performed to compare the allelic distribution of snps between frda patients and controls. student-t test was used to validate the statistical significance […]

library_books

Toward a combinatorial nature of microRNA regulation in human cells

2012
Nucleic Acids Res
PMCID: 3479204
PMID: 22904063
DOI: 10.1093/nar/gks759

[…] called mdbs: (i) targetscan database (); (ii) microcosm that is based on the miranda algorithm (); (iii) pictar, according to species conservation scheme (); (iv) diana–microt (); (v) pita (); (vi) mirz (); (vii) microrna.org that allows analysis on multiple mirna acting on the same gene-target, based on miranda (); (viii) mirdb resource (); (ix) targetrank (); (x) rna22 (); (xi) mami (); […]

library_books

Comparative analysis of human and mouse expression data illuminates tissue specific evolutionary patterns of miRNAs

2012
Nucleic Acids Res
PMCID: 3401464
PMID: 22457063
DOI: 10.1093/nar/gks279

[…] in this analysis., the mrna targets of human and mouse mirnas were predicted by the elmmo algorithm (). we retrieved the elmmo mirna target prediction flat files v5 (january 2011) at http://www.mirz.unibas.ch/mirnatargetpredictionbulk.php., the mapping of refseq ids to ensembl ids (release 60) was downloaded using biomart. we only considered target genes where the mirna binding site […]

library_books

Databases and resources for human small non coding RNAs

2011
Hum Genomics
PMCID: 3500172
PMID: 21504869
DOI: 10.1186/1479-7364-5-3-192

[…] and other secondary databases. in mirbase, the user can browse published mirna sequences from several species and can perform searches by name, accession number etc. another database for mirnas is mirz [] (table ), which provides analysis tools for mining various datasets from sequencing projects [] (table ) and mirna expression profiles. mirz integrates two previously developed resources, […]


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MirZ institution(s)
Biozentrum, Universität Basel and Swiss Institute of Bioinformatics, Basel, Switzerland; Fachhochschule Nordwestschweiz, Brugg, Switzerland; Fachhochschule Hagenberg, Hagenberg, Austria; Institut für Informatik, Universität Leipzig, Härtelstr., Leipzig, Germany
MirZ funding source(s)
Supported by Swiss National Fund (grant #3100A0-114001) Swiss Institute of Bioinformatics.

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