An integrated data portal for isoform-level expression, function and network analysis in the mouse. First, MIsoMine allows retrieval of top co-expressed isoforms in diverse tissues and experimental conditions based on the RNA-seq data collected from the Sequence Read Archive (SRA) database. Upon a gene/isoform query, the server will retrieve the top-correlated isoforms across different experiments as a heat map. Second, this data portal allows users to explore the function predictions and the functional network of alternatively splice isoforms.
Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA; Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI, USA
MIsoMine funding source(s)
This work is supported by National Institutes of Health grants 1R21NS082212-01 and U54ES017885.