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Protocols

MitoCarta specifications

Information


Unique identifier OMICS_08038
Name MitoCarta
Restrictions to use None
Version 2.0
Maintained Yes

Taxon


  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus

Maintainer


  • person_outline Sarah E. Calvo

Publications for MitoCarta

MitoCarta citations

 (33)
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Loss of the Mitochondrial Fatty Acid β Oxidation Protein Medium Chain Acyl Coenzyme A Dehydrogenase Disrupts Oxidative Phosphorylation Protein Complex Stability and Function

2018
Sci Rep
PMCID: 5760697
PMID: 29317722
DOI: 10.1038/s41598-017-18530-4
call_split See protocol

[…] . Missing values were imputed to values based on the distribution of the total matrix with downshift of 1.8 and width of 0.3. Mitochondrial proteins were defined through matching of gene names to the Mitocarta2.0 dataset. A modified two-sided t-test based on permutation-based FDR statistics was performed (FDR < 0.01, S0 = 1) between experimental groups and the negative logarithmic p-values were pl […]

library_books

Ribosomal Protein S6 Phosphorylation Is Involved in Novelty Induced Locomotion, Synaptic Plasticity and mRNA Translation

2017
PMCID: 5742586
PMID: 29311811
DOI: 10.3389/fnmol.2017.00419

[…] ar GO terms when compared to those identified in our previous analysis (Figures ).To further analyze the mitochondria-related genes dysregulation, we performed a hierarchical classification using the MitoCarta 2.0 inventory (Calvo et al., ). Indeed, among the 1071 mitochondria-related genes identified by RNAseq, 160 genes were differentially regulated in the heavy polysomal fraction between genoty […]

library_books

The interactome of intact mitochondria by cross linking mass spectrometry provides evidence for coexisting respiratory supercomplexes*

2017
PMCID: 5795388
PMID: 29222160
DOI: 10.1074/mcp.RA117.000470

[…] e proteome and filtered for proteins that show at least two unique Lys-Lys connections to known mitochondrial proteins. This analysis yielded four proteins that are currently not present in the mouse MitoCarta 2.0 database: Mmaa, Junb, Stau1, and Mum1 (Supplementary Data). Mmaa has been reported previously as a binding partner of mitochondrial methylmalonyl-CoA mutase (). Our cross-linking results […]

library_books

The Mitonuclear Dimension of Neanderthal and Denisovan Ancestry in Modern Human Genomes

2017
Genome Biol Evol
PMCID: 5509035
DOI: 10.1093/gbe/evx114

[…] estimates were produced for European populations, Asian populations, and a combined European/Asian data set in the original analysis (). We used the set of high-confidence N-mt genes (“Tmito”) in the MitoCarta 2.0 classification () to compare rates of introgression against all other nuclear protein-coding genes. We separated these high-confidence N-mt genes into two groups, distinguishing a subset […]

library_books

Charting organellar importomes by quantitative mass spectrometry

2017
Nat Commun
PMCID: 5436138
PMID: 28485388
DOI: 10.1038/ncomms15272

[…] itochondrial reference set comprising 1,238 proteins are provided in . The non-mitochondrial reference proteome comprising 1,542 proteins included proteins used as such before to define the T. brucei MitoCarta as well as proteins of the flagellar proteome and cytosolic ribosomal proteins less proteins with a predicted mitochondrial targeting sequence as determined by TargetP 1.1 (http://www.cbs.dt […]

library_books

Live cell mapping of organelle associated RNAs via proximity biotinylation combined with protein RNA crosslinking

2017
eLife
PMCID: 5730372
PMID: 29239719
DOI: 10.7554/eLife.29224.031

[…] 12, and log2(fold enrichment)≥0.904 (determined by ROC analysis) combined with all other HEK293T-expressed genes that were predicted by Phobius as having secretory signals, but which were absent from MitoCarta (). False positive RNAs were defined as all HEK293T-expressed genes lacking secretory signals, as predicted by Phobius (), SignalP (), and TMHMM (). […]

Citations

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MitoCarta institution(s)
Howard Hughes Medical Institute and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA, USA; Broad Institute, Cambridge, MA, USA; Department of Systems Biology, Harvard Medical School, Boston, MA, USA
MitoCarta funding source(s)
National Institutes of Health [GM0077465]

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