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Protocols

MitoMiner specifications

Information


Unique identifier OMICS_04553
Name MitoMiner
Restrictions to use None
Community driven No
Data access Application programming interface
User data submission Not allowed
Version 4.0
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline Alan J. Robinson

Additional information


http://mitominer.mrc-mbu.cam.ac.uk/support/tutorials

Publications for MitoMiner

MitoMiner citations

 (9)
library_books

Extreme genome diversity in the hyper prevalent parasitic eukaryote Blastocystis

2017
PLoS Biol
PMCID: 5608401
PMID: 28892507
DOI: 10.1371/journal.pbio.2003769

[…] ts retrieved from the nr database at NCBI were surveyed for any mitochondrial annotation and manually investigated. (3) All gene models and translated transcripts were queried against a local curated MitoMiner data set [] and significant hits (e-value < 1e-10) were further investigated. (4) Finally, a local MRO protein data set from various anaerobic protists including Pygsuia biforma, T. vaginali […]

call_split

Identification and quantification of protein S nitrosation by nitrite in the mouse heart during ischemia

2017
PMCID: 5582841
PMID: 28710281
DOI: 10.1074/jbc.M117.798744
call_split See protocol

[…] the percentage (100 × HeavyICAT) / (HeavyICAT + LightICAT).Information on the subcellular localization of the proteins identified and the biological processes they participated in was obtained using MitoMiner (http://mitominer.mrc-mbu.cam.ac.uk/) (). For bar charts, the data for distribution of proportion of cysteine residues against percentage S-nitrosation were generated by counting the number […]

call_split

MSTO1 is a cytoplasmic pro‐mitochondrial fusion protein, whose mutation induces myopathy and ataxia in humans

2017
PMCID: 5494519
PMID: 28554942
DOI: 10.15252/emmm.201607058
call_split See protocol

[…] h is responsible for mitochondrial function. The rare variants were filtered out based on mitochondrial gene function and disease association used a gene list, which was created by UNIPROT, NextProt, MitoMiner, and NCBI databases.As large‐scale genomic data are not available from the Hungarian population, a mutation with low minor allele frequency may be population specific. Finally, we prioritize […]

library_books

Global Proteome Changes in the Rat Diaphragm Induced by Endurance Exercise Training

2017
PLoS One
PMCID: 5279855
PMID: 28135290
DOI: 10.1371/journal.pone.0171007

[…] rial enriched fractions identified 732 (FDR <1%) proteins against the UniProt knowledgebase (UniProtKB). Of these, 302 were annotated as mitochondrial proteins in UniProtKB. When compared against the MitoMiner database of the mitochondrial proteome, 272 of the proteins were present and of those not in the MitoMiner reference set, 55 proteins possessed evidence of mitochondria origin in their GO an […]

call_split

Scale Invariant Disordered Nanotopography Promotes Hippocampal Neuron Development and Maturation with Involvement of Mechanotransductive Pathways

2016
PMCID: 5114288
PMID: 27917111
DOI: 10.3389/fncel.2016.00267
call_split See protocol

[…] , 2015) (Mi et al., ) and filtered for significant Gene Ontology terms: Biological Process (GO-SlimBP) and Pathways using a p value < 0.05.Genuine mitochondrial protein localization was determined by Mitominer, a database of the mitochondrial proteome which integrates protein data from HomoloGene, Gene Ontology, KEGG, OMIM MS/MS, GFP (green fluorescent protein) localization data and targeting sequ […]

library_books

Gender differences in white matter pathology and mitochondrial dysfunction in Alzheimer’s disease with cerebrovascular disease

2016
PMCID: 4794845
PMID: 26983404
DOI: 10.1186/s13041-016-0205-7

[…] MitoMiner was used for analysis of the mitochondria proteome []. I-Tasser suite [] was used for MBP modelling, and Pymol was used to render the 3D structure of the protein []. Using previously reporte […]


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MitoMiner institution(s)
MRC Mitochondrial Biology Unit, Wellcome Trust/MRC Building, Cambridge Biomedical Campus, Hills Road, Cambridge, UK
MitoMiner funding source(s)
Supported by Medical Research Council, UK [MC U105674181].

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