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MITOPROT specifications

Information


Unique identifier OMICS_07283
Name MITOPROT
Interface Web user interface
Restrictions to use None
Programming languages Pascal
Computer skills Basic
Stability Stable
Maintained Yes

Information


Unique identifier OMICS_07283
Name MITOPROT
Interface Command line interface
Restrictions to use None
Operating system Mac OS
Programming languages Pascal
Computer skills Advanced
Version 1.101
Stability Stable
Maintained Yes

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No version available

Publication for MITOPROT

MITOPROT citations

 (299)
library_books

Trypanosomal mitochondrial intermediate peptidase does not behave as a classical mitochondrial processing peptidase

2018
PLoS One
PMCID: 5919513
PMID: 29698456
DOI: 10.1371/journal.pone.0196474

[…] 500,000) []., putative mitochondrial pre-sequences and the cleavage sites of mpp were predicted by gavel’s consensus patterns search in the psortii program (http://psort.hgc.jp/form2.html) [,] and mitoprot ii [], using the t. brucei mitoproteome dataset []. proteins with predicted pre-sequences were further analyzed for the mip cleavage motif (f/l/i)xx(t/s/g)xxxx [] within the octapeptide […]

library_books

The mitochondrial outer membrane location of the EXD2 exonuclease contradicts its direct role in nuclear DNA repair

2018
Sci Rep
PMCID: 5876329
PMID: 29599527
DOI: 10.1038/s41598-018-23690-y

[…] proposed role in nuclear dna repair, exd2 location is predicted to be mitochondrial/cytoplasmic. cellular and mitochondrial localization prediction programs vary in their estimation. for example mitoprot ii gives a reasonably high mitochondrial probability score of 69%, psort ii gives a poor mitochondrial prediction and targetp suggests the protein is secreted. several published papers […]

library_books

Reactive oxygen species stress increases accumulation of tyrosyl DNA phsosphodiesterase 1 within mitochondria

2018
Sci Rep
PMCID: 5844879
PMID: 29523818
DOI: 10.1038/s41598-018-22547-8

[…] pathway is thus conserved between human and yeast cells., tdp1 does not contain a canonical mitochondria-targeting presequence identifiable by mitochondrial targeting sequence predictors targetp, mitoprot and mitofates (data not shown). additionally, serial truncations from either the n- or c-terminus of tdp1 did not identify a distinct mitochondrial-targeting signal; rather they identified […]

library_books

Exploring and exploiting the connection between mitochondria and the virulence of human pathogenic fungi

2018
PMCID: 5955198
PMID: 29261004
DOI: 10.1080/21505594.2017.1414133

[…] the cells is important for different aspects of virulence [,]., using bioinformatics, predictions can be made about the localization of nuclear encoded genes. for instance, we used psort ii [] and mitoprot [] on the predicted amino acid sequences of proteins of c. albicans that are required for virulence (). more than 70 proteins potentially have some level of mitochondrial localization, […]

library_books

Loss of the Drosophilam AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration

2018
PMCID: 5833341
PMID: 29467464
DOI: 10.1038/s41419-018-0365-8

[…] encoded by cg2658 contains an aaa domain (amino acid residues 377–513) and an m41 metallopeptidase domain (amino acid residues 575–785) acting as a proteolytic center (supplemental figure ). the mitoprot algorithm predicts that the n-terminal region of paraplegin contains a mitochondrial targeting sequence, and a proteomic proximity ligation study detected peptides corresponding to cg2658 […]

library_books

Silencing of Iron and Heme Related Genes Revealed a Paramount Role of Iron in the Physiology of the Hematophagous Vector Rhodnius prolixus

2018
Front Genet
PMCID: 5801409
PMID: 29456553
DOI: 10.3389/fgene.2018.00019

[…] using tmhmm version 2.0 (). signal peptide cleavage sites were predicted using signalp software version 4.1. mitochondria targeting sequences were predicted using targetp version 1.1 (; ) and mitoprot (), while gpi-modification anchors were searched using predgpi version 3.0 ()., iron responsive elements stem-loop structures were screened in the upstream regions (1200 bp) of ferritin […]


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MITOPROT institution(s)
Ecole Normale Supérieure, Laboratoire de Génétique Moléculaire, CNRS URA 1302, Paris, France
MITOPROT funding source(s)
Supported by a PFPI postdoctoral fellowship from the Ministerio de Education y Ciencia from Spain.

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