MKT pipeline

MKT specifications


Unique identifier OMICS_15192
Name MKT
Alternative name McDonald Kreitman Test
Interface Web user interface
Restrictions to use None
Input data Protein sequence file.
Input format FASTA
Output data A summary table with all the performed comparisons for each comparison, basic information is provided on the main parameters chosen and the input sequences for each region, detailed results for each performed comparison.
Output format HTML
Computer skills Basic
Stability Stable
Maintained Yes



  • person_outline Raquel Egea <>

Publication for McDonald Kreitman Test

MKT IN pipelines

PMCID: 4065255
PMID: 24727287
DOI: 10.1534/g3.114.010629

[…] program in paml 3.14 (yang 1997). we examined adaptive evolution in the protein sequences of age-1 and its neighbors by contrasting polymorphism and divergence in their coding sequence using the mcdonald-kreitman test (mcdonald and kreitman 1991)., we quantified nucleotide variation in the coding sequence of the is genes in a population of c. remanei from ohio to investigate […]

PMCID: 3493392
PMID: 23145200
DOI: 10.1371/journal.pntd.0001882

[…] and the data from zanzibar [25] were included., the genbank accession numbers for the cox1 data are jq397330–jq397399 and for the nad1 data are jq595387–595404 (see table s1)., in dnasp v5 the mcdonald_kreitman test for selection and tajima's test of neutrality were conducted on our cox1 data to investigate if there was significant selection occurring., nad1 data was only available […]

MKT institution(s)
Genomics, Bioinformatics and Evolution Group, Departament de Genètica i Microbiologia, Universitat Autonoma de Barcelona, Bellaterra (Barcelona), Spain
MKT funding source(s)
This work was supported by the Ministerio de Educacio´n y Ciencia, Spain (Grant BFU-2006-08640).

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