A software package that discovers, annotates, and genotypes non-reference mobile element insertions (MEIs) in Illumina DNA paired-end whole genome sequencing (WGS) data. MELT was first conceived as a tool to identify non-reference MEIs in large genome sequencing projects, specifically as part of the 1000 Genomes Project, and has been further optimized to run on a wide range of data types. MELT is optimized for performing discovery in a large number of individual sequencing samples using the sun grid engine (SGE). MELT also has two additional workflows: analysis without SGE (for adaptability to other parallel computing platforms) and single genome analysis. MELT is highly scalable for many different types of data.

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2 user reviews

Robert P. Ruggiero's avatar image Robert P. Ruggiero's country flag

Robert P. Ruggiero

We have been using MELT on non-model genomes and it's been great (http://journal.frontiersin.org/article/10.3389/fgene.2017.00044/full).
MELT is easy to work with and gives consistent reliable results.

Daniel Webber's avatar image

Daniel Webber

MELT was easy to install and run on SGE! It called our Alu and L1 RIPs accurately to the bp. It does a great job at integrating prior calls, and its genotyping is consistent between samples. It is more accurate then the other tools that we have used for calling transposable elements.

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MELT versioning

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MELT classification

MELT specifications

Software type:
Restrictions to use:
Academic users only
Programming languages:
Command line interface
Operating system:
Computer skills:

MELT support



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