- Unique identifier:
- Restrictions to use:
- Input format:
- Computer skills:
- Web user interface
- Input data:
- The following inputs are required: (i) query sequence of a protein; (ii) identifiers for interaction databases; (iii) type of extrapolation (based on fold, superfamily or family SCOP domain codes or none); and (iv) EVTE.
- Output data:
- The server outputs the sequences predicted to have a SCOP domain similar to that in the query. It also provides their alignments and e-values according to PSI-BLAST.
- Baldo Oliva <>
No open topic.
(Fornes et al., 2009)
ModLink+: improving fold recognition by using protein-protein interactions.
PMID: 19357100 DOI: 10.1093/bioinformatics/btp238
(Espadaler et al., 2008)
Prediction of enzyme function by combining sequence similarity and protein interactions.
PMID: 18505562 DOI: 10.1186/1471-2105-9-249
(Espadaler et al., 2005)
Detecting remotely related proteins by their interactions and sequence similarity.
Proc Natl Acad Sci U S A.
PMID: 15883372 DOI: 10.1073/pnas.0500831102
Structural Bioinformatics Lab (GRIB-IMIM), Universitat Pompeu Fabra, Parc de Recerca Biomèdica de Barcelona (PRBB), Barcelona, Spain; Structural Genomics Unit, Bioinformatics & Genomics Department, Centro de Investigación Príncipe Felipe (CIPF), Valencia, Spain; Department of Bioengineering and Therapeutic Sciences, University of California at San Francisco, San Francisco, CA, USA; Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA, USA; California Institute for Quantitative Biosciences, University of California at San Francisco, San Francisco, CA, USA
This work was supported by EU funding (IST-027703); Spanish Ministerio de Educación y Ciencia (MEC, PROFIT PSE0100000-2007-1, BIO2007/66670, BIO02008-0205, PROFIT PSE0100000-2007-1, FIT-350300- 2007-67 and FIT-350300-2006-42); Research program of the Barcelona Supercomputing Center (BSC); National Institutes of Health U54 GM074945, U54 RR022220 and R01 GM54762, Sandler Family Supporting Foundation, Mike Homer, Ron Conway, IBM, Intel, Netapp and Hewlett Packard.
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