ModuLand statistics

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Citations per year

Number of citations per year for the bioinformatics software tool ModuLand
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Tool usage distribution map

This map represents all the scientific publications referring to ModuLand per scientific context
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Associated diseases

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Protocols

ModuLand specifications

Information


Unique identifier OMICS_12239
Name ModuLand
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages Java
Computer skills Medium
Version 1.5
Stability Stable
Requirements
Cytoscape
Maintained Yes

Versioning


No version available

Maintainer


  • person_outline Máté Szalay-Bekö

Publication for ModuLand

ModuLand citations

 (23)
library_books

Two independent proteomic approaches provide a comprehensive analysis of the synovial fluid proteome response to Autologous Chondrocyte Implantation

2018
PMCID: 5932832
PMID: 29720234
DOI: 10.1186/s13075-018-1573-4

[…] erentially abundant in response to cartilage harvest in responders to ACI were used to generate interactome networks (non-inferred, 83 nodes and 118 edges; inferred, 2084 nodes and 54,007 edges). The ModuLand algorithm was applied to each of these networks to identify modules within the network that can be hierarchically ranked to identify groups of proteins that are the most fundamental in the fu […]

library_books

Identification of the functional pathways altered by placental cell exposure to high glucose: lessons from the transcript and metabolite interactome

2018
Sci Rep
PMCID: 5869594
PMID: 29588451
DOI: 10.1038/s41598-018-22535-y

[…] (non-inferred nodes), or from the genes identified through the array analysis along with their inferred interactions (inferred nodes)). Two independent mathematical algorithms, ClusterOne (v0.93) and Moduland (v2.8.3), were applied to the interactome networks in Cytoscape (v2.8.3) to identify highly connected clusters of proteins (modules) that are functionally central to the interactome network ( […]

call_split

Correlation Clustering of Stable Angina Clinical Care Patterns for 506 Thousand Patients

2017
PMCID: 5734000
PMID: 29348908
DOI: 10.1155/2017/6937194
call_split See protocol

[…] l map was produced using the Quantum GIS 2.8 open source software package []. The Louvain clustering method and smart local moving algorithm were performed using the modularity optimizer tool []. The ModuLand network modularization method was run on our network with the ModuLand plug-in of Cytoscape 2.8.2 []. […]

library_books

Multitype Network Guided Target Controllability in Phenotypically Characterized Osteosarcoma: Role of Tumor Microenvironment

2017
Front Immunol
PMCID: 5536125
PMID: 28824643
DOI: 10.3389/fimmu.2017.00918

[…] e traffic nodes and cross-linking network paths. Topological connectivity informs about the heterogeneity of networks (see ). Overlapping modules influencing community configurations were detected by ModuLand via local maxima search algorithms based on the Gradient Hill method (). Modules were determined through an influence function calculated by LinkLand and NodeLand. The overall influence of th […]

library_books

Acquired cross linker resistance associated with a novel spliced BRCA2 protein variant for molecular phenotyping of BRCA2 disruption

2017
PMCID: 5520920
PMID: 28617445
DOI: 10.1038/cddis.2017.264

[…] 3. Clustering and ‘community structure’ of modules within biological networks are known to be associated with function. To prioritize these functional components within interactome models we used the ModuLand plugin for Cytoscape 2.8.3 to determine overlapping modules, and to identify hierarchical structures within the model, thus enabling the identification of key network elements using the hyper […]

library_books

Let 7e modulates the inflammatory response in vascular endothelial cells through ceRNA crosstalk

2017
Sci Rep
PMCID: 5307339
PMID: 28195197
DOI: 10.1038/srep42498

[…] et-7e was constructed using CoExpress v1.5 (Pearson correlation coefficient >0.99, P < 0.05). The entire network was analyzed to find core subnetworks and nodes using two plugins of Cytoscape, namely ModuLand and MCODE. The nodes/subnetworks in the intersection of the results of these two plugins were selected for further study as previously described. The functions of lncRNAs were predicted accor […]


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ModuLand institution(s)
Department of Medical Chemistry, Semmelweis University, Budapest, Hungary
ModuLand funding source(s)
EU [FP6-518230, TÁMOP-4.2.2/B-10/1-2010-0013 and FP7-264780]; Hungarian Scientific Research Fund [OTKA K-83314 and PD-75261]; International Human Frontiers Science Program Organization; Momentum Program of the Hungarian Academy of Sciences; and residence at the Rockefeller Foundation Bellagio Center

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