Morpheus statistics

info info

Citations per year


Popular tool citations

chevron_left PTM identification chevron_right

Tool usage distribution map

Tool usage distribution map
info info

Associated diseases

Associated diseases
Want to access the full stats & trends on this tool?


Morpheus specifications


Unique identifier OMICS_26445
Name Morpheus
Software type Application/Script
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages C#
License MIT License
Computer skills Advanced
Version 272
Stability Stable
Maintained Yes




No version available


  • person_outline Lloyd Smith <>

Publications for Morpheus

Morpheus citations


Full length mRNA sequencing uncovers a widespread coupling between transcription initiation and mRNA processing

PMCID: 5877393
PMID: 29598823
DOI: 10.1186/s13059-018-1418-0

[…] were concatenated with gencode version 19 and protein sequences representing common mass spectrometry (ms) contaminants, creating a customized fasta file (i.e. proteomics search database). the morpheus software (version 131) was employed for ms searching of the custom database against the mcf-7 thermo raw files obtained from the study by geiger et al. []. unknown precursor charge state […]


Covariation of Peptide Abundances Accurately Reflects Protein Concentration Differences*

PMCID: 5417831
PMID: 28302922
DOI: 10.1074/mcp.O117.067728

[…] uniprot () reference proteome database (6720 yeast protein sequences of release 2015_12, 91618 human protein sequences of release 2015_07, and the sequence of bsa uniprot_id p02769) using morpheus search engine (ver. 165) (). carbamidomethylation of cysteine was set as a fixed modification, and oxidation of methionine was considered as a variable modification. the target-decoy […]


Performance Investigation of Proteomic Identification by HCD/CID Fragmentations in Combination with High/Low Resolution Detectors on a Tribrid, High Field Orbitrap Instrument

PMCID: 4966894
PMID: 27472422
DOI: 10.1371/journal.pone.0160160

[…] sensitivity, reproducibility and convenience for proteomics., with the rapid development of ms instruments, database search engines such as sequest[], mascot[], omssa[], myrimatch[], andromeda[], morpheus[], ms-gf+[], and ms amanda[] are subsequently developed to interpret the different types of spectra generated by ms. to achieve confident and accurate ms-based identification, […]


Faster and more accurate graphical model identification of tandem mass spectra using trellises

PMCID: 4908353
PMID: 27307634
DOI: 10.1093/bioinformatics/btw269

[…] we describe how to apply trellises to any scoring function expressible as a dgm. this includes linear scoring functions such as the sequest xcorr (), the score functions employed by x!tandem (), morpheus (), ms-gf+‚ÄČ() and omssa (), as well non-linear methods such as our recently proposed dbn for rapid identification of peptides (drip; )., for common ms/ms application settings, we prove […]


DeMix Workflow for Efficient Identification of Cofragmented Peptides in High Resolution Data dependent Tandem Mass Spectrometry*

PMCID: 4223503
PMID: 25100859
DOI: 10.1074/mcp.O114.038877

[…] remain chimeric. processing such spectra requires a search engine tolerant to the presence of unassigned peaks, as such peaks are always expected when multiple precursors cofragment. thus, we chose morpheus () as a search engine. based on the original search algorithm, we implement a reformed scoring scheme: morpheus-as (advanced scoring). it inherits all the basic principles from morpheus […]

Want to access the full list of citations?
Morpheus institution(s)
Department of Chemistry, University of Wisconsin, Madison, WI, USA; Department of Biochemistry, University of Wisconsin, Madison, WI, USA
Morpheus funding source(s)
Supported by National Institutes of Health Grant Nos. P50HG004952, U54DK093467, P01GM081629, and R01GM103315 and by the NIH Genomic Sciences Training Program T32HG002760 and the National Institute of Diabetes and Digestive Kidney Diseases Grant Nos.R01DK058037, R24DK091207, and R01DK066369.

Morpheus reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review Morpheus