Digital pathology, the practice of pathology using digitized images of pathologic specimens, has been transformed in recent years by the development of whole-slide imaging systems, which allow for the evaluation and interpretation of digital images of entire histologic sections. Applications of whole-slide imaging include rapid transmission of pathologic data for consultations and collaborations, standardization and distribution of pathologic materials for education, tissue specimen archiving, and image analysis of histologic specimens. Histologic image analysis allows for the acquisition of objective measurements of histomorphologic, histochemical, and immunohistochemical properties of tissue sections, increasing both the quantity and quality of data obtained from histologic assessments.
An automatic analysis of complete whole slide images (WSIs) to determine significant morphological and immunohistochemical features of Hodgkin lymphoma (HL) cells and their spatial distribution in the lymph node tissue under three different medical conditions: lymphadenitis (LA) and two types of HL. The method can be extended for different immuno cell types, their shapes and localizations as well as their interactions.
Allows users to streamline the quantitative analysis of root growth and architecture of complex root systems. SmartRoot is able to capture, store, present, and process data that are linked to location. This tool uses several algorithms designed for root tracing and has been validated on a range of image spatial resolution, noise, and contrast.
Meets the growing need for a user-friendly, extensible, open-source solution for digital pathology and whole slide image analysis. QuPath provides researchers with powerful batch-processing and scripting functionality, and an extensible platform with which to develop and share new algorithms to analyze complex tissue images. It aims to help improve the speed, objectivity and reproducibility of digital pathology analysis and biomarker interpretation.
A real time virtual microscopy technique for interactive analysis of super high resolution microscopic images over internet on standard desktops, laptops or mobile devices. VirtualMicroscopy technique is demonstrated to perform as fast as using a microscopy locally without any delay to assess gigapixel ultra high resolution image data through wired or wireless internet by a Tablet or a standard PC. More importantly, VirtualMicroscopy enables analysis of super high resolution microscopic image across sites and time and allows multi-person analysis at the same time, which greatly speed up data analysis process and reduces miscommunication among scientists and doctors.
Calculates the stained areas in a Masson Trichrome stained slide as well as the adipose tissue area. FibroQuant is a method for systematic high resolution digital quantification of different tissue types in the heart. This method of fibrosis quantification can be used for several applications like the determination of the fibrosis pattern in the heart could provide an important link for genotype-phenotype relationships in genetic cardiomyopathies.
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