MotionCor2 statistics

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Citations per year

Number of citations per year for the bioinformatics software tool MotionCor2

Tool usage distribution map

This map represents all the scientific publications referring to MotionCor2 per scientific context
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Associated diseases

This word cloud represents MotionCor2 usage per disease context

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MotionCor2 specifications


Unique identifier OMICS_17198
Name MotionCor2
Software type Package/Module
Interface Command line interface
Operating system Unix/Linux, Mac OS, Windows
Computer skills Advanced
Version 1302017
Stability Stable
Maintained Yes




No version available



  • person_outline Shawn Zheng

Publication for MotionCor2

MotionCor2 citations


Structure and mechanism of the two component α helical pore forming toxin YaxAB

Nat Commun
PMCID: 5935710
PMID: 29728606
DOI: 10.1038/s41467-018-04139-2

[…] The image processing workflow was performed with RELION 2.1. Image stacks were motion corrected with the program MotionCor2, after which the contrast transfer function values were estimated and corrected using Kai Zhang’s Gctf. 1009 particles were manually picked to create templates for autopicking. 178,149 part […]


Structural basis for energy transduction by respiratory alternative complex III

Nat Commun
PMCID: 5928083
PMID: 29712914
DOI: 10.1038/s41467-018-04141-8
call_split See protocol

[…] A set of 2479 movies was collected. Whole-image drift correction and dose weighting of each movie were performed using MotionCor2. Particles were picked manually using EMAN Boxer or automatically by template matching in Gautomatch (by Kai Zhang, MRC-LMB Cambridge, UK), and the micrograph-based CTF was determined using […]


Cryo EM reveals the structural basis of microtubule depolymerization by kinesin 13s

Nat Commun
PMCID: 5916938
PMID: 29695795
DOI: 10.1038/s41467-018-04044-8
call_split See protocol

[…] Movie frames were aligned with motioncor2 (v01-30-2017) using default parameters, generating both dose-weighted and non-dose weighted sums. CTF parameters per micrographs were estimated with Gctf (v0.50) on aligned and non-dose-wei […]


Cryo EM structure of infectious bronchitis coronavirus spike protein reveals structural and functional evolution of coronavirus spike proteins

PLoS Pathog
PMCID: 5933801
PMID: 29684066
DOI: 10.1371/journal.ppat.1007009
call_split See protocol

[…] nated in 50 frames of 200 ms exposure. Data collection statistics are summarized in .For data processing, whole frames in each movie were corrected for beam-induced motion and dose compensation using MotionCor2 [] and ~1,400 best images were manually selected (we manually discarded micrographs with only carbon field of view or thick ice after motion correction as well as micrographs with defocus p […]


Structural basis of epilepsy related ligand–receptor complex LGI1–ADAM22

Nat Commun
PMCID: 5906670
PMID: 29670100
DOI: 10.1038/s41467-018-03947-w
call_split See protocol

[…] h a total electron dose of 50 e−1 per Å2 at a pixel size of 0.785 Å per pixel. The defocus range of the data set was set to a range of −1.5 – −3.5 μm.Movie processing was performed using the software MotionCor2 and CTFFIND4. After the particle picking performed with Gautomatch ( for the particles with 200 Å diameter, image processing was performed with RELION2, […]


Structural mechanism for nucleotide driven remodeling of the AAA ATPase unfoldase in the activated human 26S proteasome

Nat Commun
PMCID: 5893597
PMID: 29636472
DOI: 10.1038/s41467-018-03785-w
call_split See protocol

[…] their gain using a gain reference recorded within 2 days of the acquired movie, after which they were shifted and summed to generate a single micrograph that was corrected for overall drift using the MotionCor2 program. Each drift-corrected micrograph was used for the determination of the actual defocus of the micrograph using the CTFFind3 program. Reference-free 2D classification was carried out […]

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MotionCor2 institution(s)
Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, CA, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA
MotionCor2 funding source(s)
This work was supported in part by grants from National Institute of Health (R01GM031627, P01GM111126, P50GM082250, R01GM082893 and R01GM098672).

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