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mOTU specifications


Unique identifier OMICS_08419
Name mOTU
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


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Publication for mOTU

mOTU citations


Similarity of the dog and human gut microbiomes in gene content and response to diet

PMCID: 5907387
PMID: 29669589
DOI: 10.1186/s40168-018-0450-3

[…] by the script., to determine the total microbial species composition of each stool sample, for both taxa previously identified and those yet to be isolated and characterized, motu-lgs were constructed as described by []. in brief, a non-redundant database of single copy marker genes (mgs), extracted from reference genomes as well as those assembled from canine and human […]


Subspecies in the global human gut microbiome

Mol Syst Biol
PMCID: 5740502
PMID: 29242367
DOI: 10.15252/msb.20177589

[…] ) protocols for speci clusters (mende et al, ). throughout the manuscript, we used speci clusters at the species level related via the ncbi taxonomy database as a taxonomic reference. additionally, motu abundances were also determined using standard mocat procedures (sunagawa et al, ), but exclusively used to estimate species diversity ()., for calling genomic variants, all metagenomic […]


Enhancing the Resolution of Rumen Microbial Classification from Metatranscriptomic Data Using Kraken and Mothur

Front Microbiol
PMCID: 5725470
PMID: 29270165
DOI: 10.3389/fmicb.2017.02445

[…] () (e.g., clark – ; gottcha – ; kraken – ; mg-rast – ), and (2) programs that target a set of marker genes (), also known as clustering-first approaches () (e.g., qiime – ; mothur – ; metaphlan – ; motu – ). in the assignment-first tools, all reads are assigned to the lowest taxonomy unit (lower common ancestor-lca) within a reference database based on their annotations, […]


Bacteriophage Distributions and Temporal Variability in the Ocean’s Interior

PMCID: 5705922
PMID: 29184020
DOI: 10.1128/mBio.01903-17

[…] a bacterium. to generate copy number per cellular genome, coverages of prophage and phage markers were normalized to the average coverage of 10 universal single-copy bacterial marker genes, called motu profiling (, )., sequence data are available at ncbi under bioproject no. prjna352737 and at, citation luo e, aylward fo, mende dr, delong ef. 2017. […]


Analyses of gut microbiota and plasma bile acids enable stratification of patients for antidiabetic treatment

Nat Commun
PMCID: 5702614
PMID: 29176714
DOI: 10.1038/s41467-017-01682-2

[…] this observation, both gene count and shannon index decreased after acarbose treatment, but not after glipizide treatment (fig. ). analysis of species-level molecular operational taxonomic unit (motu) profiles demonstrated that acarbose led to significant changes in the relative abundances of 69 motus (paired wilcoxon rank-sum test, q < 0.01; fig. ; supplementary table ); glipizide […]


Functional implications of microbial and viral gut metagenome changes in early stage L DOPA naïve Parkinson’s disease patients

Genome Med
PMCID: 5408370
PMID: 28449715
DOI: 10.1186/s13073-017-0428-y

[…] dividing each feature by the respective total sample sum and transformed with log10(x + 1), where x is the normalized feature coverage as calculated in the motus algorithm. for species and motu level analysis, we made the filtering options more explicit to exclude spurious correlations: from the abundance matrix features were removed that were absent in more than ten samples, had less […]

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mOTU institution(s)
European Molecular Biology Laboratory, Heidelberg, Germany

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