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MPA specifications


Unique identifier OMICS_07730
Name MPA
Alternative name MetaProteomeAnalyzer
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Java
License Apache License version 2.0
Computer skills Advanced
Version 1.0.4
Stability Stable
Maintained Yes


No version available



  • person_outline Erdmann Rapp

Publications for MetaProteomeAnalyzer

MPA citations


Disseminating Metaproteomic Informatics Capabilities and Knowledge Using the Galaxy P Framework

PMCID: 5874766
PMID: 29385081
DOI: 10.3390/proteomes6010007

[…] nalysis [].During the metaproteomics contribution-fest, a number of new tools and extensions to new tools were considered for deployment in Galaxy. For example, taxonomy classification tools from the MetaProteomeAnalyzer [] were considered, which process peptides identified via multiple database searching engines using information from the UniProt and National Center for Biotechnology Information […]


MetaGOmics: A Web Based Tool for Peptide Centric Functional and Taxonomic Analysis of Metaproteomics Data

PMCID: 5874761
PMID: 29280960
DOI: 10.3390/proteomes6010002

[…] ualization tools for MEGAN rely on RefSeq (NCBI) annotations and were designed for metagenomics data and utilizes full sequence information, such as an assembled gene or gene product (i.e., protein). MetaProteomeAnalyzer (MPA) [] is a complete metaproteomics pipeline spanning initial database search through final visualization. To deal with the issues associated with protein inference-based analys […]


Assessing species biomass contributions in microbial communities via metaproteomics

Nat Commun
PMCID: 5691128
PMID: 29146960
DOI: 10.1038/s41467-017-01544-x

[…] t should make it possible to transfer the approach to many other platforms, including some recently developed software pipelines addressing the protein inference problem in metaproteomics such as The MetaProteomeAnalyzer and Prophane. In this manuscript, we highlight the most crucial considerations for developing concrete methods for metaproteomics-based biomass assessment (e.g., protein inference […]


Metaproteomic analysis of human gut microbiota: where are we heading?

J Biomed Sci
PMCID: 5469034
PMID: 28606141
DOI: 10.1186/s12929-017-0342-z
call_split See protocol

[…] articularly useful to reduce sample complexity and improve protein identification. The final and fairly demanding stage for metaproteomics is data analysis. Several software tools such as Pipasic [], MetaProteomeAnalyzer [] and Unipept [] have been developed to facilitate metaproteomic data analysis. One of the key elements for a successful metaproteomic study is the availability of a relevant dat […]


The impact of sequence database choice on metaproteomic results in gut microbiota studies

PMCID: 5037606
PMID: 27671352
DOI: 10.1186/s40168-016-0196-8

[…] Peptide identification was carried out using three bioinformatic platforms: MetaProteomeAnalyzer (MPA; v.1.0.6) [], MaxQuant (MQ; v. [], and Proteome Discoverer™ (PD; v.; Thermo Scientific). For MPA analysis, X!Tandem [] was used as search engine (precursor io […]


Soil and leaf litter metaproteomics—a brief guideline from sampling to understanding

PMCID: 5026301
PMID: 27549116
DOI: 10.1093/femsec/fiw180

[…] y automated workflow for both (i) functional analyses using various resources (COG/KOG, TIGRFAMs and PFAMs) and (ii) LCA-based taxonomic assessment ( (Schneider et al. ). In addition, MetaProteomeAnalyzer software is a tool that features four freely available DB search algorithms (X!Tandem, OMSSA, Crux, InsPect), and is also highly suitable for comprehensive analysis and visualizat […]


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MPA institution(s)
Max Planck Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany

MPA review

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Anonymous user #4572's avatar image No country

Anonymous user #4572

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Hi there,
The download for the portable version does not include the viewer. So, i downloaded both separately. However, the viewer will allow the import of only mpa files while the portable version 1.0.5 only allows the importation of mgf and dat files.
Is it possible to change mgf to mpa format??