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MPMP specifications

Information


Unique identifier OMICS_02714
Name MPMP
Alternative name Malaria Parasite Metabolic Pathways
Restrictions to use None
Community driven No
Data access Browse
User data submission Allowed
Maintained Yes

Taxon


  • Invertebrates
    • Plasmodium falciparum

Documentation


Maintainer


  • person_outline Hagai Ginsburg

Publication for Malaria Parasite Metabolic Pathways

MPMP citations

 (7)
library_books

Comparative transcriptomics of female and male gametocytes in Plasmodium berghei and the evolution of sex in alveolates

2017
BMC Genomics
PMCID: 5604118
PMID: 28923023
DOI: 10.1186/s12864-017-4100-0

[…] and removing the maximum size. We used previously-published P. berghei lists of genes affected by DOZI [] and AP2-G/AP2-G2 []. Metabolic pathways were obtained using P. falciparum data available from Malaria Parasite Metabolic Pathways [], which were then mapped to syntenic orthologues in P. berghei.Motifs were detected using DREME [], running discriminative mode, and scanning the given strand onl […]

library_books

Malaria Parasite Infected Erythrocytes Secrete PfCK1, the Plasmodium Homologue of the Pleiotropic Protein Kinase Casein Kinase 1

2015
PLoS One
PMCID: 4668060
PMID: 26629826
DOI: 10.1371/journal.pone.0139591

[…] ty interactors based on threshold values (see ) in the volcano plot analysis were listed () and matched against the pathways described in the “Metabolic pathways of Malaria Parasites” website (http://mpmp.huji.ac.il; analyses were performed with the September 2013 version). As expected from the pleiotropic nature described for CK1 orthologues in many eukaryotic systems, proteins involved in a larg […]

library_books

Discovery 2: an interactive resource for the rational selection and comparison of putative drug target proteins in malaria

2013
Malar J
PMCID: 3637051
PMID: 23537208
DOI: 10.1186/1475-2875-12-116

[…] Homo sapiens were downloaded from the MODBASE database, which contains automatically generated homology models as part of the MODELER project []. Pathway information was obtained from KEGG PATHWAYS, MPMP (which is the primary malaria metabolic pathways site) [] and Reactome []. Proteins were assigned pathway information by creating links to the pathways in the different databases they are involve […]

library_books

QTL Analysis Using SNP Markers Developed by Next Generation Sequencing for Identification of Candidate Genes Controlling 4 Methylthio 3 Butenyl Glucosinolate Contents in Roots of Radish, Raphanus sativus L

2013
PLoS One
PMCID: 3538544
PMID: 23308250
DOI: 10.1371/journal.pone.0053541

[…] Genomic DNAs from 189 and 174 plants of the two F2 populations, which were prepared by the modified CTAB method, were analyzed by a modified dot-blot-SNP genotyping method, the MPMP-dot-blot-SNP method, following Li et al. First, 30 primer pairs of SNP markers were separated into six groups by MultiPLX 2.0 (five primer pairs per group). Next, the probe hybridization conditi […]

library_books

Involvement of Plasmodium falciparum protein kinase CK2 in the chromatin assembly pathway

2012
BMC Biol
PMCID: 3296614
PMID: 22293287
DOI: 10.1186/1741-7007-10-5

[…] inct from those described here for the PfCK2β subunits, lending support to the specificity of the approach. Potential PfCK2 interactors were found in 17 out of 18 metabolic processes described on the MPMP website. Many processes displayed only a very small number of hits; whether or not these represent genuine interactors will require in-depth investigations of each individual case.By contrast, ot […]

library_books

Extensive Chromosome Homoeology among Brassiceae Species Were Revealed by Comparative Genetic Mapping with High Density EST Based SNP Markers in Radish (Raphanus sativus L.)‡

2011
PMCID: 3190960
PMID: 21816873
DOI: 10.1093/dnares/dsr027

[…] CTAB method. In order to achieve cost-effective and high-efficiency SNP genotyping, a dot-blot-SNP method combining multiplex PCR and a mixed probe was developed and named multiplex PCR–mixed probe (MPMP) dot-blot analysis. First, 36 primer pairs of SNP markers were grouped into six by MultiPLX 2.0 and were assigned to six lines in a table. Secondly, hybridization conditions of probes of the mark […]

Citations

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MPMP institution(s)
Department of Biological Chemistry, Institute of Life Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel; Computational Bioscience Research Center, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia; Biological and Environmental Sciences and Engineering (BESE) Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia
MPMP funding source(s)
Supported by the Computation Authority of The Hebrew University of Jerusalem, Israel, by the World Health Organization (WHO) Special Program for Research and Training in Tropical Diseases (TDR), by the Israel Academy of Sciences and Humanities, and by OzEMalaR and has received support in the past from BioMalPar and from EviMalaR.

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