MRM-DIFF specifications


Unique identifier OMICS_25201
Alternative name Multiple Reaction Monitoring-based DIFFerential
Software type Application/Script
Interface Graphical user interface
Restrictions to use None
Input format ABF,mzML
Operating system Windows
Programming languages C#
Computer skills Medium
Stability Stable
Maintained Yes


No version available



  • person_outline Hiroshi Tsugawa

Publication for Multiple Reaction Monitoring-based DIFFerential

MRM-DIFF citation


From chromatogram to analyte to metabolite. How to pick horses for courses from the massive web resources for mass spectral plant metabolomics

PMCID: 5499862
PMID: 28520864
DOI: 10.1093/gigascience/gix037

[…] sBank of North America; MPA-RF: Model Population Analysis–Random Forests; MPEA: Metabolite Pathway Enrichment Analysis; MPMR: Medicinal Plant Metabolomic Resources; MRM: multiple reaction monitoring; MRM-DIFF: Multiple Reaction Monitoring–Based Differential Analysis; MRMPROBS: Multiple Reaction Monitoring–Based Probabilistic System; MS: mass spectrometry; MS/MS: tandem mass spectrometry; MS2T: MS/ […]

MRM-DIFF institution(s)
Metabolome Informatics Research Team, Metabolomics Research Group, RIKEN Center for Sustainable Resource Science, Yokohama, Japan; Department of Biotechnology, Graduate School of Engineering, Osaka University, Suita, Osaka, Japan; Reifycs Inc., Tokyo, Japan; National Institute of Genetics, Shizuoka, Japan
MRM-DIFF funding source(s)
Supported by the NSF-JST Strategic International Collaborative Research Program (SICORP) for JP-US Metabolomics, the Japan Science and Technology Agency (JST)-Core Research for Evolutionary Science and Technology (JST-CREST), the Development of Systems and Technology for Advanced Measurement and Analysis Project (JST), and the Advanced Low Carbon Technology Research and Development Program (JST), and a grant-in-aid for young scientists (B) 25871136 and 24700455.

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