mrSNP protocols

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mrSNP specifications

Information


Unique identifier OMICS_03509
Name mrSNP
Interface Web user interface
Restrictions to use None
Programming languages Javascript, PHP, Python
Computer skills Basic
Stability No
Maintained No

Publication for mrSNP

mrSNP in pipeline

2017
PMCID: 5579249
PMID: 28860459
DOI: 10.1038/s41598-017-10207-2

[…] luciferase reporter system to test the possible impact of these snps on the regulation of gene expression mediated by mirnas, as previously described. the prediction tools funcpred, mirwalk, mirsnp, mrsnp, mirdsnp, mirnasnp and rnahybrid were used to select mirnas which binding sites in plcb1 is potentially affected by these snps. we chose the best predictions for each snp: for rs1047383, […]


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mrSNP in publications

 (6)
PMCID: 5579249
PMID: 28860459
DOI: 10.1038/s41598-017-10207-2

[…] luciferase reporter system to test the possible impact of these snps on the regulation of gene expression mediated by mirnas, as previously described. the prediction tools funcpred, mirwalk, mirsnp, mrsnp, mirdsnp, mirnasnp and rnahybrid were used to select mirnas which binding sites in plcb1 is potentially affected by these snps. we chose the best predictions for each snp: for rs1047383, […]

PMCID: 5418741
PMID: 28171541
DOI: 10.1093/hmg/ddw317

[…] interactions will be captured. the polymirts () database identifies and annotates snps in mres which have been biologically tested, but again focuses on mirna binding regions in the 3’utr. finally, mrsnp () provides a web service for researchers working with rna-seq data to predict the impact of an snp in the 3’utr on mirna binding. while all these approaches are useful to some degree, […]

PMCID: 4880969
PMID: 27230431
DOI: 10.1186/s12863-016-0372-7

[…] of mirna binding to the 3’utr of a gene, resulting in gene dysregulation. consequently, we explored each mutation identified in the indigenous population in the following databases: mirdsnp [], mrsnp [] and rnasnp []. we plotted our results using the ucsc browser (http://genome.ucsc.edu/cgi-bin/hggateway)., this study was approved by the research committee, research ethics commitee […]

PMCID: 4828881
PMID: 27067391
DOI: 10.1186/s12920-016-0178-5

[…] the guidelines are currently silent as to the potential impact of regulatory variants affecting splicing, rna stability, and transcriptional regulation., while the mirna variant prediction program mrsnp [] was used to evaluate all of the 3’ utr variants, 41.4 % of the variants were predicted to alter the stability of the mirna-target mrna duplex for at least one mirna expressed in breast […]

PMCID: 4720480
PMID: 26789410
DOI: 10.1371/journal.pone.0145486

[…] of amino acid changes of orai1 on its protein function. mirna target sequences within the 3’-utr of orai1 mrna and the impact of the nucleotide changes within the targets was predicted using the mrsnp web service []., the experimental flow of this study was shown in . re-sequencing of the orai genomic region resulted in the identification of 69 variants (). a linkage disequilibrium analysis […]


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mrSNP institution(s)
Biomedical Informatics, Computer Science and Engineering, The Ohio State University, Columbus, OH, USA

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