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Mtreemix specifications


Unique identifier OMICS_09050
Name Mtreemix
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages C
Computer skills Advanced
Version 1.3.00
Stability Stable
Maintained Yes


No version available

Publication for Mtreemix

Mtreemix citations


Genome instability model of metastatic neuroblastoma tumorigenesis by a dictionary learning algorithm

BMC Med Genomics
PMCID: 4566396
PMID: 26358114
DOI: 10.1186/s12920-015-0132-y

[…] Once the E-FLLat approach identified the atoms, we used MTreeMix [], a software package for learning and using mixture models of oncogenic trees, to describe evolutionary processes that are characterized by the ordered accumulation of permanent genetic cha […]


Bayesian Estimation of Mixture Models with Prespecified Elements to Compare Drug Resistance in Treatment Naïve and Experienced Tuberculosis Cases

PLoS Comput Biol
PMCID: 3605089
PMID: 23555210
DOI: 10.1371/journal.pcbi.1002973

[…] ing the stability of these tree structures. For each region, a set of candidate tree structures are obtained for naïve and treatment-experienced patient from fitting 30 bootstrap samples. The program Mtreemix was used to fit Beerenwinkel's mixture model to data from naïve patients and an adaption to the Mtreemix program was used to fit our prespecified mixture model to data from treatment-experie […]


Differences in Reversion of Resistance Mutations to Wild Type under Structured Treatment Interruption and Related Increase in Replication Capacity

PLoS One
PMCID: 3031504
PMID: 21297946
DOI: 10.1371/journal.pone.0014638

[…] ility of genetic events, which is verified in this dataset as none of the mutations changed back to a variant form from the wild-type sequence over the course of the STI. We used the software package Mtreemix . […]


PyMix The Python mixture package a tool for clustering of heterogeneous biological data

BMC Bioinformatics
PMCID: 2823712
PMID: 20053276
DOI: 10.1186/1471-2105-11-9
call_split See protocol

[…] ns with MATLAB bindings. Another R package for conventional mixture analysis is the MIX package. An example for a rather specialized package would be Mtreemix which allows estimation of mixtures of mutagenic trees. In general it can be said that most of these packages focus rather narrowly on specific model typ […]

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Mtreemix institution(s)
Max Planck Institute for Informatics Stuhlsatzenhausweg, Saarbrücken, Germany; Institute of Virology, University of Cologne, Köln, Germany; Center of Advanced European Studies and Research Ludwig-Erhard-Allee 2, Germany

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