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multcomp specifications


Unique identifier OMICS_31774
Name multcomp
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
License GNU General Public License version 2.0
Computer skills Advanced
Version 1.4-8
Stability Stable
stats, graphics, mvtnorm, survival,
Source code URL
Maintained Yes


No version available



  • person_outline Torsten Hothorn

Publication for multcomp

multcomp citations


Circadian and Brain State Modulation of Network Hyperexcitability in Alzheimer’s Disease

PMCID: 5956746
PMID: 29780880
DOI: 10.1523/ENEURO.0426-17.2018

[…] ∼Genotype⁢ Treatment+Repeat⁢ ID+εwhere GenotypeTreatment was a fixed effect and RepeatID was a random effect with a random intercept. Post hoc tests for the linear model were performed using package “multcomp” with the Holm correction method (). It should be noted that while the treatment levels of control and donepezil were independent, the neostigmine treatment was applied to a sample of WT cont […]


MxB is an interferon induced restriction factor of human herpesviruses

Nat Commun
PMCID: 5958057
PMID: 29773792
DOI: 10.1038/s41467-018-04379-2

[…] of variance (ANOVA) under consideration of the assumptions of normality and homogeneity of variance. Multiple comparison tests with user-defined contrasts were performed with the glht function in the multcomp package. For non-orthogonal multiple comparisons, α-levels were corrected according to Holm’s method. […]


Magnitude processing of symbolic and non symbolic proportions: an fMRI study

PMCID: 5944011
PMID: 29747668
DOI: 10.1186/s12993-018-0141-z

[…] enward–Roger approximation for degrees of freedom []. For GLME, we ran likelihood ratio tests (LRT). These methods are available via the R package afex []. Post-hoc tests were run using the R package multcomp [] and corrected for multiple testing using the false discovery rate procedure by Benjamini and Hochberg []. […]


Genetic mapping identifies loci that influence tomato resistance against Colorado potato beetles

Sci Rep
PMCID: 5943291
PMID: 29743622
DOI: 10.1038/s41598-018-24998-5
call_split See protocol

[…] Statistical comparisons were conducted using R software. Correlation tests were conducted using the Kendall’s rank correlation tau (τ) for non-parametric data. Dunnett’s test were conducted using the Multcomp package. Graphs were made in Excel 2007. […]


Heritability of Sleep EEG Topography in Adolescence: Results from a Longitudinal Twin Study

Sci Rep
PMCID: 5943340
PMID: 29743546
DOI: 10.1038/s41598-018-25590-7

[…] eta 2, Gamma1, Gamma 2) and State (NREMS, REMS) including only data from the second assessment (Time 2). All ANOVAs were calculated with the R package afex and the post-hoc t-tests with the R package multcomp.In addition, we examined topographic distribution averaged across subjects during NREMS and REMS for 1-Hz frequency bins up to 44 Hz indicated by their upper limits (e.g., the first bin corre […]


Time to death approach to reveal chronic and cumulative toxicity of a fungicide for honeybees not revealed with the standard ten day test

Sci Rep
PMCID: 5940668
PMID: 29739960
DOI: 10.1038/s41598-018-24746-9

[…] All analyses were performed with R mainly with drc package for dose response curves (Weibull models) and toxicological endpoints estimations, the lme4 package for mixed models and the multcomp package for post-hoc multiple comparisons. All datasets, R code and detailed data analyses are provided as a public figshare repository ( […]


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multcomp institution(s)
Institut fur Statistik, Ludwig-Maximilians-Universitt Munchen, Munchen, Germany; Statistical Methodology, Clinical Information Sciences, Novartis Pharma AG, Basel, Switzerland; Texas Tech University, Lubbock, TX, USA
multcomp funding source(s)
Supported by the Bavarian State Ministry of Agriculture and Forestry under grant ST217.

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