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Multiple nucleotide sequence alignment software tools | High-throughput sequencing data analysis

Multiple sequence alignment (MSA) is a key component in almost every comparative analysis of biological sequences (DNA or proteins). Moreover, MSA reconstruction is often the first step in bioinformatic pipelines, where MSA is later used for further analyses.

Source text:
(Sela et al., 2015) GUIDANCE2: accurate detection of unreliable alignment regions accounting for the uncertainty of multiple parameters. Nucleic Acids Research.

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