Provides high quality reference alignments based on 3D structural superpositions. BAliBASE is a large scale benchmarks specifically designed for multiple sequence alignment. The alignment test cases are manually refined to ensure the correct alignment of conserved residues. The alignments are organized into reference sets designed to represent real multiple alignment problems.
Tests multiple sequence alignment methods. PREFAB is a test set which exploits methodology, test data and statistical methods that have previously been applied to alignment accuracy assessment. It contains (i) a set of reference pair alignments, (ii) samples of sequences for testing multiple alignment programs and (iii) a program of assessing the quality of work of multiple alignment programs.
Provides access to data from studies on direct coupling analysis (DCA) ability to differentiate between properly folded and misfolded structures. DCA vs. Misfolds is dedicated to studies on DCA, a method that can assist researchers in studying protein structure.
Gathers comparison of protein structures. DBAli is a database that contains pairwise and multiple structure alignments of protein structures in the Protein Data Bank (PDB). It also includes five tools that use the structural relationships in the repository. These tools can be employed to annotate the functions of protein structures whose functions are not yet known. The database also provides links to the MODBASE, LigBase, PIBASE, PDB, CATH, SCOP, PFamA, InterPro, Enzyme and GO databases.