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MULTIPOOL specifications


Unique identifier OMICS_05850
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


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Publication for MULTIPOOL

MULTIPOOL in publications

PMCID: 5851679
PMID: 29546234
DOI: 10.1126/sciadv.1701482

[…] indicate that soc is made up of materials with a wide range of turnover rates (). most radiocarbon data indicate that a large fraction of topsoil carbon cycles at decadal or faster time scales. but multipool modeling and chemical fraction methods reveal that there is also a highly resistant fraction of soc that can be up to a few thousand years old (). this highly resistant fraction […]

PMCID: 5464677
PMID: 28542190
DOI: 10.1371/journal.pgen.1006766

[…] cells (“off” and “on” segregant pools) were isolated by fluorescence-activated cell sorting (facs) and sequenced in bulk to determine the parental allele frequencies in each pool. we used the multipool software [] to determine statistical significance for allele frequency differences between off and on pools across the genome (), and called significant loci as regions where the peak […]

PMCID: 4895441
PMID: 27248513
DOI: 10.1038/ncomms11669

[…] morphologies (methods). these control pools were sequenced to an average genomic coverage of 162 × (methods)., we separately analysed the rough and control populations for each backcross using multipool and excluded any loci detected in the control pools from further consideration (methods; ; ). on the basis of this procedure, we identified between 2 and 10 loci per rough segregant, […]

PMCID: 4798298
PMID: 26990313
DOI: 10.1371/journal.pgen.1005929

[…] 126 individuals were pooled per backcross and temperature sensitivity class, and each pool was sequenced to at least 114x coverage (; ). across the six pools, eight distinct loci were detected using multipool [] (figs and ; ). seven of these loci overlapped ira2δ2933 or causal alleles that we previously identified as contributors to the phenotype at 30°c: end3by, flo83s, mga1by, mss11by, […]

PMCID: 4751556
PMID: 26637434
DOI: 10.1534/g3.115.023549

[…] regions to the previously identified runs of homozygosity (roh) regions (). effects of snps and indels were examined using snpeff software ()., to narrow down the candidate regions, we used the multipool program, ver. 0.10.2 (), which estimates a qtl locus from the allele count data using a dynamic bayesian network model. this program is known to be sensitive for fixed snps (), […]

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MULTIPOOL institution(s)
Computer Science and Artificial Intelligence Laboratory, Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, USA


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