MuPIT interactive statistics

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Citations per year

Number of citations per year for the bioinformatics software tool MuPIT interactive

Tool usage distribution map

This map represents all the scientific publications referring to MuPIT interactive per scientific context
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MuPIT interactive specifications


Unique identifier OMICS_07971
Name MuPIT interactive
Alternative name Mutation position imaging toolbox interactive
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • Primates
    • Homo sapiens


  • person_outline Rachel Karchin

Publication for Mutation position imaging toolbox interactive

MuPIT interactive citations


Evidence for adaptation of porcine Toll like receptors

PMCID: 4759233
PMID: 26701185
DOI: 10.1007/s00251-015-0892-8

[…] phylogenetic haplotype networks were constructed based on SNPs within the TLRs using Network ( Only haplotypes present in a minimum of two animals were considered. MuPIT Interactive (Niknafs et al. ) was used to map variants under selection on to three-dimensional (3D) protein structures. Swiss prot and Ensemble genome browsers were utilized to determine the fun […]


Adaptive Evolution of Toll Like Receptors (TLRs) in the Family Suidae

PLoS One
PMCID: 4404360
PMID: 25894218
DOI: 10.1371/journal.pone.0124069

[…] s study were compared to human TLR Swiss-Prot database to determine their possible link to function. Sites under positive selection were also mapped to three dimensional (3D) protein structures using MuPIT Interactive [] in order to examine their functional significance. We also determined the conservative or radical nature of amino acid changes at sites under positive selection within this study. […]

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MuPIT interactive institution(s)
Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD, USA; In Silico Solutions, Fairfax, VA, USA; Center for Biological Science and Engineering, University of California, Santa Cruz, CA, USA; Institute of Medical Genetics, School of Medcine, Cardiff University, Heath Park, Cardiff, UK
MuPIT interactive funding source(s)
Supported by National Institutes of Health CA 152432, 3U24CA143858-2S1, National Science Foundation DBI 0845275.

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