MuPIT interactive specifications


Unique identifier OMICS_07971
Name MuPIT interactive
Alternative name Mutation position imaging toolbox interactive
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • Primates
    • Homo sapiens


  • person_outline Rachel Karchin

Publication for Mutation position imaging toolbox interactive

MuPIT interactive citations


Evidence for adaptation of porcine Toll like receptors

PMCID: 4759233
PMID: 26701185
DOI: 10.1007/s00251-015-0892-8

[…] phylogenetic haplotype networks were constructed based on SNPs within the TLRs using Network ( Only haplotypes present in a minimum of two animals were considered. MuPIT Interactive (Niknafs et al. ) was used to map variants under selection on to three-dimensional (3D) protein structures. Swiss prot and Ensemble genome browsers were utilized to determine the fun […]


Adaptive Evolution of Toll Like Receptors (TLRs) in the Family Suidae

PLoS One
PMCID: 4404360
PMID: 25894218
DOI: 10.1371/journal.pone.0124069

[…] s study were compared to human TLR Swiss-Prot database to determine their possible link to function. Sites under positive selection were also mapped to three dimensional (3D) protein structures using MuPIT Interactive [] in order to examine their functional significance. We also determined the conservative or radical nature of amino acid changes at sites under positive selection within this study. […]

MuPIT interactive institution(s)
Department of Biomedical Engineering, Institute for Computational Medicine, Johns Hopkins University, Baltimore, MD, USA; In Silico Solutions, Fairfax, VA, USA; Center for Biological Science and Engineering, University of California, Santa Cruz, CA, USA; Institute of Medical Genetics, School of Medcine, Cardiff University, Heath Park, Cardiff, UK
MuPIT interactive funding source(s)
Supported by National Institutes of Health CA 152432, 3U24CA143858-2S1, National Science Foundation DBI 0845275.

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