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MUpro specifications


Unique identifier OMICS_07141
Name MUpro
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for MUpro

MUpro citations


Accurate prediction of functional, structural, and stability changes in PITX2 mutations using in silico bioinformatics algorithms

PLoS One
PMCID: 5903617
PMID: 29664915
DOI: 10.1371/journal.pone.0195971

[…] o be destabilizing by molecular modeling (L54Q, R91P, W86S, and W86C). DUET, mCSM, and I-Mutant3.0 identified 3 and iPTREE-STAB detected 2 of 7 destabilizing mutations detected by molecular modeling. MUpro and iStable were unable to identify any of the 7 destabilizing mutations predicted by molecular modeling. […]


Developmental Testicular Expression, Cloning, and Characterization of Rat HDAC6 In Silico

Biomed Res Int
PMCID: 5671680
PMID: 29201907
DOI: 10.1155/2017/5170680

[…] Bioinformatic analysis of HDAC6 was done using the MUpro, COPid, and PredictProtein tools [–]. […]


Vermont: a multi perspective visual interactive platform for mutational analysis

BMC Bioinformatics
PMCID: 5606220
PMID: 28929973
DOI: 10.1186/s12859-017-1789-3

[…] nted INPS-Multi Descriptor (MD), which complements INPS with a new predictor (INPS-3D) that exploits descriptors derived from the protein structure.iStable, proposed in [], integrates I-Mutant2.0 [], MUPRO [], AUTO-MUTE [], PoPMuSiC2.0 [], and CUPSAT [] through SVM to predict protein stability changes upon single amino acid residue mutations, and it performs better than any single method alone.DUE […]


Identification of novel mutations in congenital afibrinogenemia patients and molecular modeling of missense mutations in Pakistani population

PMCID: 5594472
PMID: 28912669
DOI: 10.1186/s12959-017-0143-3

[…] 2), ( accessed on 20th April 2015) was used to assess the possible impact of substitution on structure and function in human SNPs (Single nucleotide polymorphism). MUPRO (predictions of protein stability changes upon mutations), ( accessed on 20th April 2015) utilizes an SVM (support vector machines) model to predict the chang […]


Neuronal Encoding of Self and Others’ Head Rotation in the Macaque Dorsal Prefrontal Cortex

Sci Rep
PMCID: 5561028
PMID: 28819117
DOI: 10.1038/s41598-017-08936-5

[…] Once a neuron was isolated, macaque subjects performed a head-rotation task (HRe) (Fig. ). The monkey’s head was partially unrestrained (i.e., forces were measured through the MUPRO system, and head rotation of +/− 20° was allowed), and subjects received a piece of fruit (1 × 1 cm), positioned to their right or left, as a reward. In order to reach the food, they had to turn […]


Dynamic scaffolds for neuronal signaling: in silico analysis of the TANC protein family

Sci Rep
PMCID: 5533708
PMID: 28754924
DOI: 10.1038/s41598-017-05748-5

[…] Pathogenicity of NDD associated variants in TANC proteins was assessed using twelve different prediction tools: Align-GVGD, I-Mutant2.0, MUpro, MutationAssessor, MutationTaster, PhD-SNP, Polyphen2, PROVEAN, SIFT, SNAP2 and UMD-Predictor. […]


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MUpro institution(s)
Institute for Genomics and Bioinformatics, School of Information and Computer Sciences, University of California, Irvine, CA, USA

MUpro review

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Anonymous user #11942's avatar image No country

Anonymous user #11942

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its a very helpful tool. can anyone tell me the full form of this acronym MUPro