Assists in building large structure-guided sequence alignments of functionally diverse protein families. Mustguseal offers users possibility to download the final alignment for a local utilization. This final alignment can be operated on-line with the built-in interactive tools and further submitted to the integrated sister web-servers of Mustguseal. This operation permits users to analyze conserved, subfamily-specific, and co-evolving residues for studying a protein function and regulation.
Belozersky Institute of Physicochemical Biology, Moscow, Russia; Faculty of Bioengineering and Bioinformatics, Moscow, Russia; Faculty of Computational Mathematics and Cybernetic, Moscow, Russia; Research Computing Center of the Lomonosov Moscow State University, Moscow, Russia