Main logo
?
tutorial arrow
×
Submit new tools
Share tools covering the current topic. Provide easy-to-follow guidelines to improve their usability.
Share new tools with the community
Sign up for free to promote the availability of bioinformatics tools

Cancer mutational signature identification software tools | Genome variation analysis

Mutational signatures are patterns in the occurrence of somatic single nucleotide variants (SNVs) that can reflect underlying mutational processes.Source text:(Gehring et al., 2015) SomaticSignatures: inferring mutational signatures from…
signeR
Desktop

signeR

Provides an empirical Bayesian approach to mutational signature discovery.…

Provides an empirical Bayesian approach to mutational signature discovery. SigneR is designed to analyze single nucleotide variaton counts in cancer genomes, but can also be applied to other features…

MutaGene
Dataset

MutaGene

Permits to analyze any given set of mutations, and determines the contributions…

Permits to analyze any given set of mutations, and determines the contributions of predefined annotated mutational signatures. MutaGene is an online computational framework that constructs DNA…

SignatureEstima…
Desktop

SignatureEstimation

Serves to decompose a patient mutational profile into a linear combination of…

Serves to decompose a patient mutational profile into a linear combination of pre-defined mutational signatures. SignatureEstimation can give a profile tumor with the frequencies or the proportions…

SomaticSignatur…
Desktop

SomaticSignatures

Provides flexible, interoperable, and easy-to-use tools that identify such…

Provides flexible, interoperable, and easy-to-use tools that identify such signatures in cancer sequencing data. SomaticSignatures facilitates large-scale, cross-dataset estimation of mutational…

RGIFE
Desktop

RGIFE Ranked Guided Iterative Feature Elimination

Removes blocks of attributes rather than in a static approach. RGIFE is a…

Removes blocks of attributes rather than in a static approach. RGIFE is a heuristic method for the identification of small sets of highly predictive biomarkers. It provides higher performance in…

pmsignature
Web
Desktop

pmsignature Probabilistic Mutation signature

Methods for modelling, identifying and visualizing such mutation signatures.…

Methods for modelling, identifying and visualizing such mutation signatures. Pmsignature simplifies mutation signature models compared with existing approaches and reducing the number of parameters…

orchid
Desktop

orchid

Consists in tumor mutation management and machine learning analysis framework.…

Consists in tumor mutation management and machine learning analysis framework. Orchid allows users to manage, annotate, and analyze tumor mutations by integrating mutation data with popular…

Emu
Desktop

Emu Expectation-Maximisation inference of mutational signatures

A software tool for inferring the mutational signatures present in a number of…

A software tool for inferring the mutational signatures present in a number of cancer mutation sets. Several independent mutational processes jointly produce the observed spectrum of mutations in a…

By using OMICtools you acknowledge that you have read and accepted the terms of the end user license agreement.