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Mutationassessor

Predicts the functional impact of amino-acid substitutions in proteins, such as mutations discovered in cancer or missense polymorphisms. The functional impact is assessed based on evolutionary conservation of the affected amino acid in protein homologs. Mutationassessor has been validated on a large set (60k) of disease associated (OMIM) and polymorphic variants.

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Mutationassessor classification

  • Animals
    • Homo sapiens

Mutationassessor specifications

Interface:
Web user interface
Computer skills:
Basic
Maintained:
Yes
Restrictions to use:
None
Stability:
Stable

Mutationassessor distribution

Credits

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Publications

Institution(s)

Computational Biology Center, Memorial Sloan-Kettering Cancer Center, NY, USA

Link to literature

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