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Leucine-rich nuclear export signal prediction software tools | Protein sequence analysis

Leucine-rich nuclear export signals (NESs) are short amino acid motifs that mediate binding of cargo proteins to the nuclear export receptor CRM1, and thus contribute to regulate the localization and function of many cellular proteins. Computational…
NetNES
Web

NetNES

Allows to analyze and predict nuclear export signals. NetNES uses neural…

Allows to analyze and predict nuclear export signals. NetNES uses neural networks and hidden Markov models (HMM) and was tested on the most recently discovered Nuclear export signals (NESs) of the…

LocNES
Web

LocNES Locating Nuclear Export Signals

A Support Vector Machine (SVM) predictor that locates classical nuclear export…

A Support Vector Machine (SVM) predictor that locates classical nuclear export signals (NESs) in CRM1 cargoes. Export-Karyopherinβ CRM1 recognizes hundreds of broadly functioning proteins. Most CRM1…

NESbase
Dataset

NESbase

A database of proteins in which the presence of Leucine-rich nuclear export…

A database of proteins in which the presence of Leucine-rich nuclear export signal (NES) has been experimentally verified. It is curated from literature.

NESsential
Desktop

NESsential

A software tool to predict leucine-rich nuclear export signals from amino acid…

A software tool to predict leucine-rich nuclear export signals from amino acid sequence.

ValidNESs
Dataset

ValidNESs

A database for experimentally validated leucine-rich nuclear export signal…

A database for experimentally validated leucine-rich nuclear export signal (NES)-containing proteins. It stores metadata in two tables and provides three search functions to access these data. Once…

Wregex
Desktop
Web

Wregex Weighted regular expression

An approach for amino acid motif searching that can be used for leucine-rich…

An approach for amino acid motif searching that can be used for leucine-rich nuclear export signal (NES) prediction.

NESmapper
Desktop

NESmapper

A computational tool to predict leucine-rich nuclear export signals (NESs) by…

A computational tool to predict leucine-rich nuclear export signals (NESs) by using profiles that had been further optimized by training and combining the amino acid properties of the NES-flanking…

NESdb
Dataset

NESdb

A database that contains NES-containing CRM1 cargoes that were manually curated…

A database that contains NES-containing CRM1 cargoes that were manually curated from the published literature. It is freely available to nonprofit organizations.

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