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|Interface||Web user interface|
|Restrictions to use||None|
Publications for NetAligner
GreedyPlus: An Algorithm for the Alignment of Interface Interaction Networks
[…] ed on an explicit evolutionary model, and then the alignment is extended outwards from the seed along network edges, incorporating as many other protein pairs as possible and optimizing on the score. NetAligner, for example, assumes that interacting proteins evolve at similar rates as part of scoring edge mismatches and gaps. MaWISH formulates an evolutionary model consisting of three events: matc […]
Detecting conserved protein complexes using a dividing and matching algorithm and unequally lenient criteria for network comparison
[…] ], such as Mawish, NetworkBlast,PHUNKEE and Produles. The reason may be considering indirectly connected node pairs in one network is robust against missing interactions in original network. Although NetAligner employs more lax criteria to introduce conserved interactions, it also yields a lot of false positive conserved interactions, which reduces its performance of detecting conserved complexes. […]
The post genomic era of biological network alignment
[…] lem. Intuitively, it greedily grows a subgraph starting from a seed with maximum gain with respect to the cost function; a bad move (negative gain) is allowed in order to bypass a poor local optimum. NetAligner  is a pairwise aligner featuring pathway-to-interactome, complex-to-interactome, and interactome-to-interactome alignments. Also, it is able to perform both inter- and intra-species align […]
Increasing the precision of orthology based complex prediction through network alignment
[…] We performed all complex to interactome alignments using the NetAligner algorithm that we recently developed () and which is also available as a web server (). For all species combinations, we computed vertex and interaction conservation probabilities required […]
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