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|Interface||Web user interface|
|Restrictions to use||None|
|Input data||An amino acid sequence.|
- Homo sapiens
- person_outline NetChop Team
Publications for NetChop
Immunopharmacogenomics towards personalized cancer immunotherapy targeting neoantigens
[…] nicity in individual patients, and it has been reported that peptide–HLA complex stability might have a better correlation with the immunogenicity of the peptides. Some computational methods, such as NetChop and NetCTL, focus on predicting antigen processing and peptide transport processes., Structural‐based approaches are also important to predict the orientation of a mutated amino acid that is […]
Mapping HLA A2, A3 and B7 supertype restricted T cell epitopes in the ebolavirus proteome
[…] , among others. Earlier studies had elucidated putative T-cell epitopes of individual EBOV proteins [–] by use of bioinformatics tools, such as SYFPEITHI [, ], BIMAS [, ], IEDB [, ], NetMHCcons , NetChop , NetCTL , NetCTLpan , NetMHCpan  and NetMHCIIpan . However, the identification and analyses of T-cell epitopes from the complete ZEBOV proteome, especially in the context of HLA-sup […]
The generation of a simian adenoviral vectored HCV vaccine encoding genetically conserved gene segments to target multiple HCV genotypes
[…] Prediction of proteasomal cleavage sites was run using server NetChop 3.1, (version C-term 3.0). Epitope prediction analysis was run using online epitope prediction programs NetMHC, Syfpeithi and BIMAS with a cut-off for strong epitope binders of <0.5, >20, and […]
Neoantigen Targeting—Dawn of a New Era in Cancer Immunotherapy?
[…] en the mutational burden in tumors and the observed response came from checkpoint inhibitor studies using either PD-1/PD-L1 or CTLA-4 inhibitors. After tumor exome sequencing and data processing with NetChop and NetMHC algorithms, van Rooij et al. showed the expansion of a T cell response directed against a mutated version of ATR (ataxia teleangiectasia and rad3 related) in a melanoma patient afte […]
Exploring dengue genome to construct a multi epitope based subunit vaccine by utilizing immunoinformatics approach to battle against dengue infection
[…] icial neural networks while TAP transport efficiency was achieved by an approach based on weight matrix, while C-terminal proteasomal cleavage site was predicted by the artificial neural network from NetChop 3.1 server. Scores of all three predictions were merged together and sensitivity or specificity values can be achieved by the conversion of the threshold from the merged score. During CTL epit […]
Multilevel genomics of colorectal cancers with microsatellite instability—clinical impact of JAK1 mutations and consensus molecular subtype 1
[…] predicted to be generated by cleavage in proteasomes, the list of neoantigens was filtered to include only peptides with predicted C-terminal cleavage sites using the stand-alone software package of NetChop 3.1 . When summarizing the number of neoantigens per tumor, peptides predicted to bind to several HLA alleles were counted only once. […]
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