Determines interaction between T cell receptors (TCRs) and peptides presented by HLA-A*02:01. NetTCR leans on convolutional neural networks (CNNs). It employs the peptide and TCRb CDR3 amino acid sequences to work. This tool allows for the straight forward integration of the major histocompatibility complex (MHC) molecule or TCR alpha chain.
DTU Bioinformatics, Technical University of Denmark, Copenhagen, Denmark; DTU Nanotechnology, Technical University of Denmark, Copenhagen Denmark; La Jolla Institute for Allergy and Immunology, La Jolla, CA, USA; University of San Martin, San Martin, Argentina