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NetWalker specifications


Unique identifier OMICS_08344
Name NetWalker
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Operating system Mac OS, Windows
Computer skills Medium
Stability Stable
Maintained No


No version available


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Publications for NetWalker

NetWalker citations


Drug repurposing in idiopathic pulmonary fibrosis filtered by a bioinformatics derived composite score

Sci Rep
PMCID: 5626774
PMID: 28974751
DOI: 10.1038/s41598-017-12849-8

[…] the drug repurposing tool - cmap, of each dataset regarding their fold change (fc). to introduce a second, independent way to prioritize the most important genes related to ipf per dataset, we used netwalker, as a random walk-based approach, to construct a second list with the same number of up and down regulated genes., we separately used the two lists of up and down regulated genes […]


Multiplex serum protein analysis reveals potential mechanisms and markers of response to hyperimmune caprine serum in systemic sclerosis

PMCID: 5341430
PMID: 28270187
DOI: 10.1186/s13075-017-1252-x

[…] in 14 patients. serum or plasma samples at baseline, 26 and 52 weeks were analysed using multiplex or individual immunoassays for 41 proteins. patterns of change were analysed by clustering using netwalker 1.0, pearson coefficient and significance analysis of microarrays (sam) correction., cluster analysis, sam multiplex testing and paired comparison of individual analytes identified proteins […]


Enhanced MAPK signaling is essential for CSF3R induced leukemia

PMCID: 5537052
PMID: 28031554
DOI: 10.1038/leu.2016.376

[…] or down-regulated genes were chosen based on a p-value cut-off of 0.05. for networks, down- or up-regulated genes were used as seeds to build a coherent network using gene-connector functionality in netwalker suite()., two μg of total rna was used to synthesize cdna using superscript iii first strand synthesis kit (life technologies). q-pcrs were performed using the sybr green method […]


Metabolomic analysis of human oral cancer cells with adenylate kinase 2 or phosphorylate glycerol kinase 1 inhibition

PMCID: 5327379
PMID: 28243334
DOI: 10.7150/jca.17521

[…] from xcms online were used to generate the cloud plot . the metabolic features that showed significant changes in the cancer cells with ak2 or pgk1 knockdown were used to generate heat maps with the netwalker 1.0 (, adenylate kinases (aks) are a set of enzymes that catalyze the nucleotide phosphoryl exchange reaction. among them, ak2 is a metabolic enzyme expressed […]


Targeting KRas dependent tumor growth, circulating tumor cells and metastasis in vivo by clinically significant miR 193a 3p

PMCID: 5344721
PMID: 27669434
DOI: 10.1038/onc.2016.308

[…] lung cancer cells transfected with mir-193a-3p was determined relative to the control mirna, and a network of the top 300 downregulated interactions was determined after edge flux analysis using netwalker(, ) (http://www.netwalker to determine the potential for mir-193a-3p to regulate the resulting network through kras, we intersected the network with that of our kras signature. […]


A Long Non Coding RNA Defines an Epigenetic Checkpoint in Cardiac Hypertrophy

Nat Med
PMCID: 5053883
PMID: 27618650
DOI: 10.1038/nm.4179

[…] and visualized on the ucsc browser. gene ontology analysis was performed with david bioinformatics resources 6.7. genes changed over 1.5 fold were clustered and shown as heat map (log2 scale) using netwalker., immunoblotting analysis was performed as previously described. cells were washed twice with ice cold pbs, and harvested in protein lysis buffer (50 mm hepes [ph7.4], 150 mm nacl, 1% […]

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NetWalker institution(s)
Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA

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