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Network Alignment NETAL

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An algorithm for the global alignment of protein-protein interaction networks. NETAL uses a greedy method, based on the alignment scoring matrix, which is derived from both biological and topological information of input networks to find the best global network alignment. It outperforms other global alignment methods in terms of several measurements, such as Edge Correctness, Largest Common Connected Subgraphs and the number of common Gene Ontology terms between aligned proteins. As the running time of NETAL is much less than other available methods, NETAL can be easily expanded to multiple alignment algorithm. Furthermore, it overpowers all other existing algorithms in term of performance so that the short running time of NETAL allowed us to implement it as the first server for global alignment of protein-protein interaction networks.

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1 user review

1 user review

Kevin Davis's avatar image

Kevin Davis

I like how fast it can align big networks!

NETAL forum

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NETAL classification

NETAL specifications

Software type:
Package/Module
Restrictions to use:
None
Computer skills:
Advanced
Maintained:
Yes
Interface:
Command line interface
Operating system:
Unix/Linux
Stability:
Stable

NETAL distribution

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NETAL forum

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No open topic.

NETAL classification

NETAL specifications

Interface:
Web user interface
Computer skills:
Basic
Maintained:
Yes
Restrictions to use:
None
Stability:
Stable

Credits

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Publications

Institution(s)

Department of Computer Engineering, Sharif University of Technology, Tehran, Iran

Link to literature

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