nextflu statistics

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Associated diseases

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nextflu specifications


Unique identifier OMICS_09372
Name nextflu
Interface Web user interface
Restrictions to use None
Programming languages Javascript, Python
License GNU Affero General Public License version 3
Computer skills Basic
Stability Stable
Maintained Yes


  • Viruses
    • Influenza A virus
    • Influenza A virus (A/Puerto Rico/8/1934(H1N1))
    • Influenza B virus



  • person_outline Trevor Bedford <>

Publication for nextflu

nextflu in publications

PMCID: 5790164
PMID: 29284042
DOI: 10.1371/journal.ppat.1006749

[…] to the serial replacement of novel antigenic types in the victoria-lineage viruses (), the two antigenically-distinct clades of the yamagata-lineage co-circulate globally, alternating in dominance ( (). however, despite the divergence and counter-cyclical maintenance of yamagata-lineage clades 2 and 3 over 10 years, recent reports indicate that the incidence of clade 2 […]

PMCID: 5260787
PMID: 28117657
DOI: 10.1186/s12920-016-0230-5

[…] dynamics of antigenic evolution. the relationship between the antigenic distances based on sequences and those calculated from hi titer data was further discussed in [], where an online tool named “nextflu” was provided for real-time tracking. although those studies have obtained insightful results, most of them focus on the clusters of antigenic mutations. currently very few studies work […]

PMCID: 4817224
PMID: 26840485
DOI: 10.1038/nature16996

[…] border with guinea. crucially, we released data at regular intervals throughout this project through github, integrating our results with that of others and interactively displayed at we employed the virological web forum to discuss complex cases ( this system will continue to support the west african epidemic response and will serve […]

PMCID: 4531805
PMID: 27391693
DOI: 10.1186/s13059-015-0726-x

[…] make it easy for international teams to write to an ‘open lab notebook’ []. online tools can provide powerful evolutionary and epidemiological visualizations, such as bedford and nehrer’s nextflu, which was originally designed for influenza strain tracking and has now been adapted to integrate real-time ebola genomic datasets ( []. we have also employed […]

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nextflu institution(s)
Max Planck Institute for Developmental Biology, Tübingen, Germany; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
nextflu funding source(s)
This work was supported by the ERC though Stg-260686 and by the NIH through U54 GM111274.

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