bookmark sampleDrift Models the kinetics of different metabolites in samples over different temperature and time conditions. sampleDrift is able to correct for pre-analytical errors. It predicts pre-centrifugation temperature and time parameters. This tool was tested and approved by external validation of 111 ethylene diamine tetra-acetic acid (EDTA) plasma samples. It improves experimental data by taking into account reproducible pre-analytical, sample history-derived changes in individual metabolite levels, where handling conditions could be predicted from experimental data.