NNDB specifications


Unique identifier OMICS_03594
Alternative name Nearest Neighbor DataBase
Restrictions to use None
Maintained Yes

Publication for Nearest Neighbor DataBase

NNDB citation


A sensitivity analysis of RNA folding nearest neighbor parameters identifies a subset of free energy parameters with the greatest impact on RNA secondary structure prediction

Nucleic Acids Res
PMCID: 5449625
PMID: 28334976
DOI: 10.1093/nar/gkx170
call_split See protocol

[…] dom errors. As such, standard error is used throughout the sensitivity analysis.Using the perturbed parameter sets, new data tables for RNAstructure were generated following the rules outlined in the NNDB (). This ensured that symmetric parameters for base pairs and internal loops always had equivalent values. Additionally, the precalculated approximations, such as those for unmeasured 1 × 1, 2 × […]

NNDB institution(s)
Department of Chemistry and Center for RNA Biology, University of Rochester, Chinahester, NY, USA

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