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Norine specifications


Unique identifier OMICS_05728
Name Norine
Restrictions to use None
Maintained Yes


  • person_outline Areski Flissi

Publications for Norine

Norine citations


A strategy for the identification of patterns in the biosynthesis of nonribosomal peptides by Betaproteobacteria species

Sci Rep
PMCID: 5583390
PMID: 28871139
DOI: 10.1038/s41598-017-11314-w

[…] )”: which represents the amino acid that conferred an out of consensus moiety (unrecognized peptide side chain from antiSMASH results). PECs and POPs were normalized according to antiSMASH, KEGG, and Norine nomenclatures. […]


Discovery Strategies of Bioactive Compounds Synthesized by Nonribosomal Peptide Synthetases and Type I Polyketide Synthases Derived from Marine Microbiomes

Mar Drugs
PMCID: 4849084
PMID: 27092515
DOI: 10.3390/md14040080

[…] ster.html) [] and NRPS-PKS-substrate-predictor ( []. Prediction of putative NRPs can be complemented by using a highly informative database such as NORINE ( NORINE is a database specialized in manually curated information on 1,178 NRPs (last visited 26 January 2016). Queries may be issued on compound names, activit […]


Burkholderia genome mining for nonribosomal peptide synthetases reveals a great potential for novel siderophores and lipopeptides synthesis

PMCID: 4906002
PMID: 27060604
DOI: 10.1002/mbo3.347

[…] rid PKS‐NRPS “3100‐1300‐1500” and “6274,” named according to the protein sizes (Table , Fig. ). None of the three predicted peptides share any pattern with the known curated peptides annotated in the Norine database. We have no other clues leading to the prediction for siderophore activity or lipopeptide structure and the concerned strains are pathogenic. We can guess that the products may be invo […]


In silico methods for linking genes and secondary metabolites: The way forward

PMCID: 5640692
PMID: 29062931
DOI: 10.1016/j.synbio.2016.03.001

[…] standard and MIBiG-compliant reannotation has been carried out for approximately 400 secondary metabolite biosynthetic gene clusters. Another example of a useful database for secondary metabolites is NORINE, which has chemical structures for 1168 nonribosomal peptides. Based on bioinformatics analysis of experimentally characterized PKS and NRPS gene clusters, a number of computational methods hav […]


Phylogenetic and Functional Substrate Specificity for Endolithic Microbial Communities in Hyper Arid Environments

Front Microbiol
PMCID: 4784552
PMID: 27014224
DOI: 10.3389/fmicb.2016.00301

[…] . Similarly to the whole metagenome, we found an increased abundance of NRPS and PKS secondary metabolite biosynthetic genes and gene clusters in the Ig12 ignimbrite genome (Figure ). Searches in the NORINE database revealed that the closest chemical structures for the putative products of these gene clusters were often siderophores (Figure ). A figure linking genes products with greater than 80% […]


The secondary metabolite bioinformatics portal: Computational tools to facilitate synthetic biology of secondary metabolite production

PMCID: 5640684
PMID: 29062930
DOI: 10.1016/j.synbio.2015.12.002

[…] ins., , Signals corresponding to NRPs or NRP-analogs are detected by comparison to databases containing computationally generated fragments of known secondary metabolites (e.g., those extracted from NORINE or PubChem). Recently, iSNAP has also been extended to identify PK compounds and analogs of known molecules.The Global Natural Products Social Molecular Networking system (GNPS) provides workfl […]


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Norine institution(s)
Computer Science Laboratory of Lille (UMR USTL/CNRS 8022) and INRIA; ProBioGEM (UPRES EA 1026), University of Sciences and Technologies of Lille, Villeneuve-d'Ascq, France

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