Normalization software tools | Ribosome profiling data analysis
Ribosome profiling (Ribo-seq), a promising technology for exploring ribosome decoding rates, is characterized by the presence of infrequent high peaks in ribosome footprint density and by long alignment gaps.
Identifies mRNA sequence features that affect ribosome footprint densities globally. RUST is designed for ribo-seq data and produces a metafootprint profile that reveals the influence of mRNA features such as codons/amino acids on the relative read density in the sample across the entire ribosome and nascent peptide region.
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