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Differential expression analysis software tools | RNA sequencing

Differential expression analysis software tools | RNA sequencing

One of the main goals of RNA-seq experiments is to identify the differentially expressed genes in two or more conditions. Such genes are selected based on a combination of expression change threshold and score cutoff, which are usually based on P values generated by statistical modeling. Normalization in the context of differential analysis is essential in order to account for the presence of systematic variation between samples as well as differences in library composition.

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