NPEST specifications


Unique identifier OMICS_06113
Restrictions to use None
Maintained No

Publication for NPEST

NPEST citations


Integrated computational approach to the analysis of RNA seq data reveals new transcriptional regulators of psoriasis

PMCID: 5133374
PMID: 27811935
DOI: 10.1038/emm.2016.97

[…] fish genomes. Evidence comes from transcription start site mapping from high-throughput experimental techniques, such as CAGE and Oligocapping. The positions of the promoters were validated using the NPEST algorithm. We identified 16‚ÄČ542 Homo sapiens promoters with corresponding RNA-seq gene expression measurements in lesional and non-lesional skin.The relative expression (R.E.) values for every g […]


Toward high resolution population genomics using archaeological samples

PMCID: 4991838
PMID: 27436340
DOI: 10.1093/dnares/dsw029

[…] y of NGS reads near the TSS of active genes would be lower than at silent genes. Based on read density at known TSSs and DHSs from the ENCODE project and using de novo methods of TSS prediction (e.g. NPEST or TSSer), it is possible to sort TSSs according to transcriptional activity of corresponding genes. In the near future, it may be feasible to quantitatively reconstruct gene expression patterns […]

NPEST institution(s)
Children's Hospital Los Angeles and Keck School of Medicine, University of Southern California, Los Angeles, CA, USA

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