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Nucleosome positioning software tools | MNase sequencing data analysis

Nucleosome positioning software tools | MNase sequencing data analysis Nucleosomes consisting of approximately 146 base pairs (bp) of DNA wrapped around a histone octamer are the fundamental structural units of chromatin in metazoans. The translational positioning of nucleosomes along DNA is implicated in profoundly influencing gene expression. Thus, defining the nucleosome positioning and occupancy is critical to understand the mechanisms of regulation of transcription by chromatin.
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