OD-seq specifications


Unique identifier OMICS_09758
Name OD-seq
Software type Package/Module
Interface Command line interface
Restrictions to use None
Input data OD-seq can take a MSA, distance matrix or set of unaligned sequences as input.
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes




No version available


  • person_outline Higgins Desmond G.

Publication for OD-seq

OD-seq citation


LEON BIS: multiple alignment evaluation of sequence neighbours using a Bayesian inference system

BMC Bioinformatics
PMCID: 4936259
PMID: 27387560
DOI: 10.1186/s12859-016-1146-y

[…] methods exist that estimate homology based on a multiple sequence alignment, but these methods generally look for features shared amongst all or most of the sequences. Alternatively, methods such as OD-seq have been developed to identify outlier sequences and remove them completely from the alignment. Nevertheless, today’s complex alignments require a more precise definition of conserved sequence […]

OD-seq institution(s)
UCD Conway Institute of Biomolecular and Biomedical Sciences, University College Dublin, Dublin, Ireland
OD-seq funding source(s)
Funding was provided by Science Foundation Ireland to DGH through PI grant 11/PI/1034.

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