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ODCs specifications


Unique identifier OMICS_11834
Name ODCs
Alternative name Orphan Disease Connections
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes


  • person_outline Monica Chagoyen

Publication for Orphan Disease Connections

ODCs citations


Lactobacillus rossiae strain isolated from sourdough produces putrescine from arginine

Sci Rep
PMCID: 5838238
PMID: 29507315
DOI: 10.1038/s41598-018-22309-6

[…] of L. brevis IOEB 9906.The phylogenetic tree (Fig. ) constructed - based on the clustalW alignment of those ODC proteins that have been described involved in the production of putrescine - showed the ODCs of LABs to be closely related (except that of L. saerimneri 30a).Figure 2 […]


A Minimally invasive Blood derived Biomarker of Oligodendrocyte Cell loss in Multiple Sclerosis

PMCID: 5006601
PMID: 27381476
DOI: 10.1016/j.ebiom.2016.06.031

[…] Evaluation of O4+ fraction purity was performed by fluorescence-activated cell sorting (FACS) analysis. Magnetically purified ODCs were washed twice and suspended in FACS buffer containing anti-O4 labeled antibody or isotype control and analyzed using an Accuri FACS analyzer (BD Biosciences, San Diego, CA). FACS data was ana […]


Oxalate Metabolising Genes of the White Rot Fungus Dichomitus squalens Are Differentially Induced on Wood and at High Proton Concentration

PLoS One
PMCID: 3914892
PMID: 24505339
DOI: 10.1371/journal.pone.0087959

[…] amino acid alignment. Amino acid sequences were aligned using MAFFT and manually corrected in MEGA 5 . Three bacterial ODC-like proteins were used as an outgroup for the phylogenetic tree of fungal ODCs, while three plant FDHs were used as an outgroup for the FDH tree. The phylogeny was computed using three algorithms to provide a high level of confidence. The maximum likelihood (ML) statistical […]


Cortical Depth Dependent Functional Responses in Humans at 7T: Improved Specificity with 3D GRASE

PLoS One
PMCID: 3606277
PMID: 23533682
DOI: 10.1371/journal.pone.0060514

[…] sponse (measured as the sharpness of the tuning curves) is generally higher for 3D GRASE than GE () despite a larger overall response in GE, consistent with columnar specificity measurements in human ODCs . Further, the non-specific superficial draining veins appear to deteriorate the quality of the responses of GE signal towards the surface, while the specificity of 3D GRASE remains unaltered thr […]


Structural Insight into DFMO Resistant Ornithine Decarboxylase from Entamoeba histolytica: An Inkling to Adaptive Evolution

PLoS One
PMCID: 3543441
PMID: 23326423
DOI: 10.1371/journal.pone.0053397
call_split See protocol

[…] The sequence of EhODC, along with other functional ODCs and AZI were retrieved from NCBI database . Multiple sequence alignment and phylogenetic tree of these sequences were obtained using ClustalW for evolutionary variation analysis. […]


Biochemical, Mutational and In Silico Structural Evidence for a Functional Dimeric Form of the Ornithine Decarboxylase from Entamoeba histolytica

PLoS Negl Trop Dis
PMCID: 3289617
PMID: 22389745
DOI: 10.1371/journal.pntd.0001559

[…] uence . K2d results were found to be in agreement with the result of SOPMA showing 33% α-helix and 25% β-sheet content (). These estimations are in accordance with the available crystal structures of ODCs and also with the molecular model for EhODC, which was generated by homology modeling in the present study. These results reveal that EhODC contains an α/β tertiary structure and has the overall […]


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ODCs institution(s)
Escuela Politecnica Superior, Universidad Autonoma de Madrid, Madrid, Spain; Computational Systems Biology Group, National Centre for Biotechnology, Madrid, Spain

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