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Olorin | Combining gene flow with exome sequencing in large family studies of complex disease

An interactive filtering tool for next generation sequencing data coming from the study of large complex disease pedigrees. Olorin is a tool which integrates gene flow output from Merlin and next generation sequencing data. Users can interactively filter and prioritize variants based on haplotype sharing across different sets of selected individuals and allele frequency in reference datasets.

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Olorin classification

  • Animals
    • Homo sapiens

Olorin specifications

Unique identifier:
Command line interface, Graphical user interface
Operating system:
Unix/Linux, Mac OS, Windows
MIT License
Software type:
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Olorin distribution


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Olorin support


  • James A. Morris <>


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Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK

Funding source(s)

Wellcome Trust grant number WT098051

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