OptFlux statistics

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OptFlux specifications


Unique identifier OMICS_05174
Name OptFlux
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Windows
Computer skills Advanced
Stability Stable
Maintained Yes


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  • person_outline Isabel Rocha <>

Publication for OptFlux

OptFlux in publications

PMCID: 5776761
PMID: 29357933
DOI: 10.1186/s12934-018-0860-8

[…] table , based on the entner–doudoroff (ed) pathway, the pentose phosphate (pp) pathway, the tca cycle, as well as the alginate and p3hb biosynthetic pathways. fba simulations were performed using the optflux 3.3, an open-source and modular software for in silico metabolic engineering []. maximizing cellular growth rate was used as the objective function for all fba simulations.table 3 , expression […]

PMCID: 5779732
PMID: 29468126
DOI: 10.1016/j.meteno.2016.07.003

[…] system gams 24.4.1 (gams development corporation, washington, dc) as described in ., optgene was performed on the ijn678 reaction subset using the “evolutionary optimization” algorithm in the optflux software ()., minimization of metabolic adjustment (moma) was used to predict the flux distributions of mutant strains (). the fitness metric was biomass-product coupled yield (bpcy), […]

PMCID: 4870247
PMID: 27242701
DOI: 10.3389/fmicb.2016.00673

[…] of equations is loaded into matlab® (the mathworks, inc., natick, massachusetts, united states.) using the cobra toolbox. model loading and simulation can be also done in software packages such as optflux (rocha et al., ). in the following step, (ii), excel and r software are used to record the metabolite concentration curves observed in experimental cultures and then calculate specific rates […]

PMCID: 5779720
PMID: 29468121
DOI: 10.1016/j.meteno.2016.05.002

[…] by the authors in the supplementary material. yeast 6.06 () was downloaded in sbml format from the project's website: http://sourceforge.net/projects/yeast/files/., each model was imported into optflux 3.07 () and the in silico environmental conditions were set to mimic minimal growth media supplemented with glucose under fully-aerobic conditions (ammonia: unconstrained uptake, phosphate: […]

PMCID: 4717628
PMID: 26783098
DOI: 10.1186/s12934-016-0416-8

[…] syhymep is a web-based application implemented in java and runs on the apache tomcat web server (ver. 7.0.64., http://tomcat.apache.org/). fba was performed with our original command line tool using optflux libraries, which use glpk (gnu linear programming kit) as a linear programming solver []., , ts performed the experiment; ts, to, and ak designed the research; ts wrote […]

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OptFlux institution(s)
IBB-Institute for Biotechnology and Bioengineering/Centre of Biological Engineering, University of Minho, Campus de Gualtar, Braga, Portugal

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